CleanAmp™ Primers for Hot Start PCR - hot start, hot start pcr, modified primers, primer-dimer, mispriming, pcr primer, cleanamp, pcr, qpcr, end point pcr, diagnostic, diagnostic oligo, turbo, precision, diagnostic kit

REQUEST A CATALOG

Oligonucleotides Nucleotides DNA Synthesis Reagents

Account Log In/New Account OligoBuilder^® Online Ordering International Distributors

TriLink Products

Oligonucleotides

Modified Nucleotides

DNA Synthesis Reagents

Products Index

OligoBuilder® Ordering

Our Catalog

Join the TriLink Community

Search our Bibliography

HOME > PRODUCTS > OLIGONUCLEOTIDES > CLEANAMP™ PRIMERS FOR HOT START PCR

CleanAmp™ Primers ^{__________________________________________________________________________}
The Next Generation of “Hot Start” PCR

Novel Technology

CleanAmp™ Primers contain thermolabile chemical modifications that allow for primer-based “hot start” activation in PCR. These modifications prevent primer extension at the lower temperatures of PCR set-up and manipulation. A “hot start” thermal activation step removes the modification and generates the corresponding unmodified primer, which supports amplification of the undesired target.

CleanAmp™ Primer Modifications

Can be introduced into any primer sequence
Improve amplification specificity using any PCR enzyme
Minimize primer dimers
Reduce mis-priming
Can be employed in versatile PCR-based applications

Which CleanAmp™ Primer is right for my application?

CleanAmp™ Primers are available in two forms, which vary in the rate of thermal activation. CleanAmp™ Turbo II modifications are released more quickly than those for CleanAmp™ Precision II. The two different speeds of primer activation are suited for a number of PCR-based applications.

CleanAmp™ Turbo II Primers	CleanAmp™ Precision II Primers
Fast cycling (<45 min. total cycling time)	Standard cycling (>45 min. total cycling time)
Multiplexed PCR	Reverse-transcription PCR
Improved amplicon yield	Improved specificity and limit of detection
Reduced mis-priming/primer dimer formation	Greatest reduction in mis-priming/primer dimer formation

Technical Resources
R&D Poster- April 2008	MSDS
Product Manual	Product Brochure
CleanAmp™ Application Note

CleanAmp™ is a trademark of TriLink BioTechnologies, Inc. This product or portions thereof is covered by TriLink pending Patent Applications, US2007281308 and WO2007139723, and US Patent 6762298 licensed from the Department of Health and Human Services. CleanAmp™ products are sold exclusively for R & D use by the purchaser. They may not be used for clinical or diagnostic purposes and they may not be resold, distributed or re-packaged. No license is granted or implied with the purchase of this product. It may be necessary to obtain a license for certain patented applications in which the product is used.

PRODUCTS | ORDERING | TECHNICAL SUPPORT | NEWS | ABOUT TRILINK