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Applications Supported:
Stem Cell Reprogramming
Custom qPCR Standards
Transient Zinc Finger Nuclease Expression
Gene Therapy Research
RNA Structural Studies and RNase Protection Assays
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TriLink is an industry leader in manufacturing high quality modified RNA, both chemically synthesized RNA and long RNA by transcription. TriLink's reaction-ready RNA transcription service features custom synthesis, including custom messenger RNA (mRNA), as well as stocked reporter gene and expression factor mRNA. TriLink's RNA transcript synthesis advantages include:
- Custom tailored support to meet specific application or program needs from template amplification to a wide variety of modifications, treatments and purification options.
- High quality, unique products at highly competitive prices due to in-house manufacturing of key raw materials.
- Wide range of synthesis scales yielding µgrams to hundreds of milligrams.
- Fully traceable documentation system.
| Transfection with TriLink's EGFP mRNA Results in Robust EGFP Expression in HEK-293 Cells. |
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Image courtesy of Jiehua Zhou, John Rossi Lab, City of Hope. |
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| Transfection with TriLink’s modified mRNA results in higher expression rates and lower toxicity. Pseudo-U and 5-Methyl-C modified mRNA results in increased expression and reduced toxicity relative to unmodified mRNA in BJ fibroblasts, cells commonly used for iPSC generation. |
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Image courtesy of Mirus Bio LLC. |
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