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Oligonucleotides

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  Diagnostic Services Designing and developing specifications for your diagnostic kit components can be an impossible challenge without a nucleic acid chemist on your team. Since 1996 we have been applying our unique nucleic acid chemistry expertise to our customers’ technical barriers.

Your Perfect Partner
PartnersWe will work closely with you to tailor the manufacturing process to your specific program needs. Our extensive research in randomization optimization for the Roche NimbleGen platform is a great example of how we can make your product even better. Our process development and scale-up research in support of the ABI SOLiD™ System oligonucleotides is another example of what our technical expertise can do for you. To learn how our ingenuity can work for you, please contact our technical support team.

A Customized Program
Whether you are ordering your first oligonucleotide or are ready to set up a full supply program, TriLink is the right supplier for you. Material can be ordered in nmoles all the way up to multiple grams. We offer several levels of purification to meet your needs. Our crude material ranges from 60% - 80% pure. We will not ship any purified material unless it meets our 85% purity minimum without your request and approval. Greater purity can be achieved with additional purification steps at your request.

QC Analyses Available Additional Services Available
  • PAGE analysis & gel densitometry
  • Mass spectroscopy
  • RP/AX-HPLC analysis
  • Synthesis report
  • Other assays available
  • Custom labeling & documentation
  • Label control
  • Research & development
  • Manufacturing process optimization

QSR Manufacturing
Every product made at TriLink is manufactured under QSR, whether it is for diagnostics, therapeutics or research. At TriLink our top priority has always been manufacturing the highest quality products for our customers. We will work with you to develop, document and validate processes and materials for your specific program. We will then manufacture your product under a quality system based on the FDA's Quality System Regulations (QSR) and the ISO 9001:2008 standard. We also offer programs compliant with the FDA 21CFR 820 regulation for ASR manufacturing.

Benefits of Manufacturing under QSR: Program Guidelines Include:
  • Manufacturing process validation
  • Optimized synthesis & purification protocols
  • Locked process & specification documentation
  • Separate batch record for each compound
  • Dedicated program review
  • All personnel trained in QSR compliance
  • SOPs & central records handling
  • Supplier validation & traceable raw material
  • Controlled access to dedicated laboratories

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