Randomers Randomers have become an essential tool in diagnostic research. They can help identify a gene that codes for a protein of interest when the specific sequence is unknown or amplify a genetic target to generate a pool of all available sequences.
Commercial assays have been developed that use randomers to detect a single base mismatch polymorphism, as well as map chromosomal differences, most commonly deletions. These sensitive applications require oligos of random sequence, consistent base composition and minimal lot to lot variability.
TriLink has done extensive research and development to ensure our randomer oligos meet these crucial specifications, see our Randomer Oligonucleotides Article. We stock the more commonly requested randomers, as well as provide custom randomer synthesis. Each and every lot of our validated products are tested by Roche NimbleGen prior to release. This is to ensure that they pass Roche NimbleGen's specifications for use in their array systems. TriLink is the only outside supplier of these oligonucleotides at this time. We are also the only supplier of pack sizes above 2 OD260 units, including Roche NimbleGen. If you are interested in a custom synthesis please use our online ordering system OligoBuilder® or contact us.
