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Therapeutic oligos

TriLink specializes in mid-scale synthesis of both DNA and RNA oligonucleotides. We understand how important the material required for pre-clinical, diagnostic and therapeutic studies is to our customers.
Our pricing is very competitive and we are committed to providing the highest quality products. We offer quantities from 50 mg to 10 g. If you require more than 10 g, we recommend our alliance partner Avecia.
All products are analyzed by PAGE, HPLC and MS. Turn around time varies based on sequence, purification and quantity requested. Please inquire. Additional services available include modifications, radioactive labeling, process development and cGMP and QSR manufacturing.

Radioactive Labeling

TriLink offers 35S and 3H labeling of phosphodiester and phosphorothioate oligonucleotides. Radioactively labeled oligonucleotides are often required by the FDA for an IND (investigative new drug) filing, which is an early step in the process of drug approval. Our compounds are prepared manually and HPLC purified to greater than 90% full length product to ensure the highest quality. Our process typically yields greater than 95% radio-isotopically pure material. Our extensive experience in preparing radioactively labeled oligonucleotides specifically for pre-clinical
trials ensures you will receive a superior product.
Read the Press Release >>


The TriLink-Avecia Alliance

The TriLink-Avecia Alliance allows easy transition from R&D and pre-clinical studies to clinical trials and commercial manufacturing of therapeutic oligonucleotides. Read More >>

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