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Technical Articles The TriLink Team has developed the following library of technical articles as a resource to our customers. Is there a related topic you would like to learn more about? Let us know.

DNA Synthesis and Reagents
	A Short History of Oligonucleotide Synthesis
	Troubleshooting the Synthesis of Modified Oligonucleotides
	DNA Linker and Spacer Reagents and Their Utility
	Phthalimidyl Protected 3' Amine Reagent Enhances Yield of Conjugated Product
	Comparison of Deprotection Methods for the Phthalimidyl Amino CPGs
	DADE: A Pre-Activated Carboxyl Linker, Applications and Methods
	Use of Custom Synthesized Phosphoramidite Reagents
Oligonucleotide Applications
	An Antisense Oligonucleotide Primer
	Randomer Oligonucleotides
	The Use of Radioactively Labeled Oligonucleotides for Pharmacokinetic Studies
Technical Resources
	Quenchers
	Pseudo-complementary Nucleic Acids
	Understanding Oligonucleotide Synthetic Yields
	Thermostability of Modified Oligonucleotide Duplexes
	When is my Oligonucleotide Pure Enough?
Oligo Data and Tables
	An Introduction to Extinction Coefficients and Molecular Weights of Oligos
	Oligonucleotide Extinction Coefficient Formula and Molecular Weight Calculations
Nucleoside Triphosphates
	Enzymatic Incorporation of Biotin-16-AA-dNTPs Presentation
	PCR Incorporation of Modified dNTPs: The Substrate Properties of Biotinylated dNTPs
	Modified Nucleoside Triphosphate Applications: An Overview of the SELEX Process
	Enzymatic Activity of Selected Nucleoside 5'-Triphosphates and Their Analogs
	³¹P Chemical Shifts in NMR Spectra of Nucleotide Derivatives
	Nucleoside Triphosphate Bibliography
CleanAmp™ Resources
	CleanAmp™ Primers Application Note
	Procedure for Synthesis of CleanAmp™ Primers
	Successful Synthesis with CleanAmp™ Amidites
	Improved PCR Specificity With Hot Start PCR Primers
	Improved PCR flexibility with Hot Start dNTPs
	Robust PCR amplification of GC-rich targets with Hot Start 7-deaza-dGTP

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