2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate)

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N-8009
Alpha Thiol ddATP, 1-Thio-ddATP
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SKU Unit Size Price Qty
N-8009-1 1 µmole
$91.00
N-8009-5 5 µmole
$425.00
N-8009-10 10 µmole
$728.00
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Description

2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddATP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.

Product Details

Catalog No N-8009
Purity ≥90% by AX-HPLC
Extinction Coefficient 15,400 Lmol-1cm-1 at 258 nm
Molecular Formula C10H16N5O10P3S (free acid)
Molecular Weight 491.20 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H2O
Recommended Storage -20°C or below
Other Name(s) Alpha Thiol ddATP, 1-Thio-ddATP
Backbone 5'-O-(1-Thiotriphosphate)
Base Analog(s) Adenosine
Sugar Type(s) 2'-3'-Dideoxy
Nucleotide Category Phosphate Modified

Technical Documents



Certificate of Analysis


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