2-Aminopurine-2'-deoxyriboside-Triphosphate - (N-2004)
2-Aminopurine-drTP
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N-2004
Description
2-Aminopurine-2'-deoxyribose is a fluorescent purine analog used as a marker in nucleic acid research. It is also used in mutagenesis studies, as it base pairs with both thymine and cytosine residues.
Product details
| Catalog No | N-2004 |
|---|---|
| Purity | ≥90% by AX-HPLC |
| Extinction Coefficient | 6,422 Lmol-1cm-1 at 303 nm |
| Molecular Formula | C10H16N5O12P3 (free acid) |
| Molecular Weight | 491.10 g/mole (free acid) |
| Salt Form | Li+ |
| Concentration | 100 mM |
| Buffer | H2O |
| Recommended Storage | -20°C or below |
| Other Name(s) | 2-Aminopurine-drTP |
| Application | Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies |
| Backbone | 5'-Triphosphate |
| Base Analog(s) | Adenosine, Guanosine |
| Sugar Type(s) | DNA |
| Nucleotide Category | Base Modified DNA |
Technical documents
N-2004 Safety Data Sheet
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Intellectual property
Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission of Seller. No license under any patent or other intellectual property right of Seller or its licensors is granted or implied by the purchase unless otherwise provided in writing.
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References
- Roettger, Michelle P.; Fiala, Kevin A.; Sompalli, Susmitha; Dong, Yuxia; Suo, Zucai . Pre-Steady-State Kinetic Studies of the Fidelity of Human DNA Polymerase â€ÂÂ
- Bakhtina, Marina; Roettger, Michelle P.; Tsai, Ming-Daw . Contribution of the Reverse Rate of the Conformational Step to Polymerase Fidelityâ€ÂÂ
- Patro, Jennifer N.; Urban, Milan; Kuchta, Robert D. . Role of the 2-amino group of purines during dNTP polymerization by human DNA polymerase alpha.
- Trostler, Michael; Delier, Alison; Beckman, Jeff; Urban, Milan; Patro, Jennifer N.; Spratt, Thomas E.; Beese, Lorena S.; Kuchta, Robert D. . Discrimination between right and wrong purine dNTPs by DNA polymerase I from Bacillus stearothermophilus.
