Back to top

2'-Deoxy-P-nucleoside-5'-Triphosphate - (N-2037)

dPTP
In stock
default
N-2037
Product SKU Unit Size Price Qty
N-2037
N-2037-1 1 µmole
$151.00
N-2037-5 5 µmole
$657.00
N-2037-10 10 µmole
$1,243.00
Description
2'-Deoxy-P-nucleoside is a degenerate base which behaves as a universal pyrimidine and therefore base pairs with both adenine and guanine. This feature makes it a powerful tool in mutagenesis studies.
Product details
Catalog No N-2037
Purity ≥90% by AX-HPLC
Extinction Coefficient 6,473 Lmol-1cm-1 at 293 nm
Molecular Formula C11H18N3O14P3 (free acid)
Molecular Weight 509.20 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H2O
Recommended Storage -20°C or below
Other Name(s) dPTP
Application Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Backbone 5'-Triphosphate
Base Analog(s) Cytidine
Sugar Type(s) DNA
Nucleotide Category Base Modified DNA
Technical documents

N-2037 Safety Data Sheet

Products faqs

Ask an Expert

Certificate of analysis

CoA search tool

Intellectual property

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission from TriLink No license under any patent or other intellectual property right of TriLink or its licensors is granted or implied by the purchase unless otherwise provided in writing.

TriLink does not warrant that the use or sale of the products delivered hereunder will not infringe the claims of any United States or other patents or patents pending covering the use of the product alone or in combination with other products or in the operation of any process. All and any use of TriLink product is the purchaser's sole responsibility.

References
  1. Espinosa, J. C.; Tercero, J. A.; Rubio, M. A.; Jiménez, A. . The pur7 gene from the puromycin biosynthetic pur cluster of Streptomyces alboniger encodes a nudix hydrolase.
  2. Keith, Jonathan M.; Cochran, Duncan A. E.; Lala, Gita H.; Adams, Peter; Bryant, Darryn; Mitchelson, Keith R. . Unlocking hidden genomic sequence
  3. Kim, Hyun Jin; Eichinger, Andreas; Skerra, Arne . High-affinity recognition of lanthanide(III) chelate complexes by a reprogrammed human lipocalin 2.
  4. Wang, Zhirui; Kim, Geun-Bae; Woo, Jung-Hee; Liu, Yuan Yi; Mathias, Askale; Stavrou, Scott; Neville, David M. Jr . Improvement of a recombinant anti-monkey anti-CD3 diphtheria toxin based immunotoxin by yeast display affinity maturation of the scFv.
  5. Reineks, Edmunds Z.; Berdis, Anthony J. . Evaluating the contribution of base stacking during translesion DNA replication.
  6. Hackel, Benjamin J.; Kapila, Atul; Wittrup, K. Dane . Picomolar affinity fibronectin domains engineered utilizing loop length diversity, recursive mutagenesis, and loop shuffling.
  7. Gera, Nimish; Hill, Andrew B.; White, Dalon P.; Carbonell, Ruben G.; Rao, Balaji M. . Design of pH sensitive binding proteins from the hyperthermophilic Sso7d scaffold.
  8. Tillotson, Benjamin J.; de Larrinoa, Iñigo F.; Skinner, Colin A.; Klavas, Derek M.; Shusta, Eric V. . Antibody affinity maturation using yeast display with detergent-solubilized membrane proteins as antigen sources.
  9. Burns, Michael L.; Malott, Thomas M.; Metcalf, Kevin J.; Hackel, Benjamin J.; Chan, Jonah R.; Shusta, Eric V. . Directed evolution of brain-derived neurotrophic factor for improved folding and expression in Saccharomyces cerevisiae.
  10. Petrie, Katherine L.; Joyce, Gerald F. . Limits of neutral drift: lessons from the in vitro evolution of two ribozymes.
  11. Julian, Mark C.; Lee, Christine C.; Tiller, Kathryn E.; Rabia, Lilia A.; Day, Evan K.; Schick, Arthur J. 3rd; Tessier, Peter M. . Co-evolution of affinity and stability of grafted amyloid-motif domain antibodies.
  12. Yang, Gloria; Hong, Nansook; Baier, Florian; Jackson, Colin J.; Tokuriki, Nobuhiko . Conformational Tinkering Drives Evolution of a Promiscuous Activity through Indirect Mutational Effects.
  13. Chen, Kuang-Hua; Liu, Shihui; Leysath, Clinton E.; Miller-Randolph, Sharmina; Zhang, Yi; Fattah, Rasem; Bugge, Thomas H.; Leppla, Stephen H. . Anthrax Toxin Protective Antigen Variants That Selectively Utilize either the CMG2 or TEM8 Receptors for Cellular Uptake and Tumor Targeting.
  14. Gronemeyer, Thomas; Chollet, Julian; Werner, Stefan; Glomb, Oliver; Bäuerle, Anne; Johnsson, Nils . A Split-Ubiquitin Based Strategy Selecting for Protein Complex-Interfering Mutations.
  15. Kapur, Shiven; Silverman, Adam P.; Ye, Anne Z.; Papo, Niv; Jindal, Darren; Blumenkranz, Mark S.; Cochran, Jennifer R. . Engineered ligand-based VEGFR antagonists with increased receptor binding affinity more effectively inhibit angiogenesis.
  16. Bratulic, Sinisa; Toll-Riera, Macarena; Wagner, Andreas . Mistranslation can enhance fitness through purging of deleterious mutations.
  17. Kauke, Monique J.; Traxlmayr, Michael W.; Parker, Jillian A.; Kiefer, Jonathan D.; Knihtila, Ryan; McGee, John; Verdine, Greg; Mattos, Carla; Wittrup, K. Dane . An engineered protein antagonist of K-Ras/B-Raf interaction.
  18. Kruziki, Max A.; Sarma, Vidur; Hackel, Benjamin J. . Constrained Combinatorial Libraries of Gp2 Proteins Enhance Discovery of PD-L1 Binders.
  19. Sirois, Allison R.; Deny, Daniela A.; Baierl, Samantha R.; George, Katia S.; Moore, Sarah J. . Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding.
  20. Hussain, Mahmud; Angus, Steven P.; Kuhlman, Brian . Engineering a Protein Binder Specific for p38α with Interface Expansion.
  21. Tei, R;Baskin, JM; . Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds
  22. Hunter, SA;McIntosh, BJ;Shi, Y;Sperberg, RAP;Funatogawa, C;Labanieh, L;Soon, E;Wastyk, HC;Mehta, N;Carter, C;Hunter, T;Cochran, JR; . An engineered ligand trap inhibits leukemia inhibitory factor as pancreatic cancer treatment strategy
  23. Zheng, J;Guo, N;Wagner, A; . Mistranslation reduces mutation load in evolving proteins through negative epistasis with DNA mutations
  24. Zheng, J;Bratulic, S;Lischer, HEL;Wagner, A; . Mistranslation can promote the exploration of alternative evolutionary trajectories in enzyme evolution
  25. Tomek, KJ;Volkel, K;Indermaur, EW;Tuck, JM;Keung, AJ; . Promiscuous molecules for smarter file operations in DNA-based data storage
Show more