2'-O-Methyluridine-5'-Triphosphate - (N-1018)
2'-O-Methyl-UTP, 2'OMe-UTP
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N-1018
Product details
Catalog No | N-1018 |
---|---|
Purity | ≥90% by AX-HPLC |
Extinction Coefficient | 10,100 Lmol-1cm-1 at 262 nm |
Molecular Formula | C10H17N2O15P3 (free acid) |
Molecular Weight | 498.10 g/mole (free acid) |
Salt Form | Li+ |
Concentration | 100 mM |
Buffer | H2O |
Recommended Storage | -20°C or below |
Other Name(s) | 2'-O-Methyl-UTP, 2'OMe-UTP |
Application | Aptamers, Epigenetics/DNA Damage |
Backbone | 5'-Triphosphate |
Base Analog(s) | Uridine |
Sugar Type(s) | 2'-O-Methyl |
Nucleotide Category | Sugar Modified |
Technical documents
N-1018 Safety Data Sheet
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Certificate of analysis
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Intellectual property
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References
- Karikó, Katalin; Muramatsu, Hiromi; Welsh, Frank A.; Ludwig, János; Kato, Hiroki; Akira, Shizuo; Weissman, Drew . Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability.
- Xiao, Zeyu; Levy-Nissenbaum, Etgar; Alexis, Frank; Lupták, Andrej; Teply, Benjamin A.; Chan, Juliana M.; Shi, Jinjun; Digga, Elise; Cheng, Judy; Langer, Robert; Farokhzad, Omid C. . Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection.
- Kanwar, Jagat R.; Roy, Kislay; Kanwar, Rupinder K. . Chimeric aptamers in cancer cell-targeted drug delivery.
- Lauridsen, Lasse H.; Rothnagel, Joseph A.; Veedu, Rakesh N. . Enzymatic recognition of 2'-modified ribonucleoside 5'-triphosphates: towards the evolution of versatile aptamers.
- Green, Nathaniel M.; Moody, Krishna-Sulayman; Debatis, Michelle; Marshak-Rothstein, Ann . Activation of autoreactive B cells by endogenous TLR7 and TLR3 RNA ligands.
- Lai, Zijuan; Tsugawa, Hiroshi; Wohlgemuth, Gert; Mehta, Sajjan; Mueller, Matthew; Zheng, Yuxuan; Ogiwara, Atsushi; Meissen, John; Showalter, Megan; Takeuchi, Kohei; Kind, Tobias; Beal, Peter; Arita, Masanori; Fiehn, Oliver . Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics.