5-Methyluridine-5'-Triphosphate - (N-1024)
5-Methyl-UTP, 5-Me-UTP, 5-mUTP
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N-1024
Product details
Catalog No | N-1024 |
---|---|
Purity | ≥90% by AX-HPLC |
Extinction Coefficient | 9,650 Lmol-1cm-1 at 267 nm |
Molecular Formula | C10H17N2O15P3 (free acid) |
Molecular Weight | 498.10 g/mole (free acid) |
Salt Form | Li+ |
Concentration | 100 mM |
Buffer | H2O |
Recommended Storage | -20°C or below |
Other Name(s) | 5-Methyl-UTP, 5-Me-UTP, 5-mUTP |
Application | Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies |
Backbone | 5'-Triphosphate |
Base Analog(s) | Thymidine, Uridine |
Sugar Type(s) | RNA |
Nucleotide Category | Base Modified RNA |
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References
- Nguyen, Allen; Zhao, Connie; Dorris, David; Mazumder, Abhijit . Quantitative assessment of the use of modified nucleoside triphosphates in expression profiling: differential effects on signal intensities and impacts on expression ratios.
- Karikó, Katalin; Muramatsu, Hiromi; Welsh, Frank A.; Ludwig, János; Kato, Hiroki; Akira, Shizuo; Weissman, Drew . Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability.
- Karikó, Katalin; Buckstein, Michael; Ni, Houping; Weissman, Drew . Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA.
- Anderson, Bart R.; Muramatsu, Hiromi; Nallagatla, Subba R.; Bevilacqua, Philip C.; Sansing, Lauren H.; Weissman, Drew; Karikó, Katalin . Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation.
- Schein, Catherine H.; Oezguen, Numan; van der Heden van Noort, Gerbrand J.; Filippov, Dmitri V.; Paul, Aniko; Kumar, Eric; Braun, Werner . NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU).
- Motorin, Yuri; Helm, Mark . RNA nucleotide methylation.
- Lai, Zijuan; Tsugawa, Hiroshi; Wohlgemuth, Gert; Mehta, Sajjan; Mueller, Matthew; Zheng, Yuxuan; Ogiwara, Atsushi; Meissen, John; Showalter, Megan; Takeuchi, Kohei; Kind, Tobias; Beal, Peter; Arita, Masanori; Fiehn, Oliver . Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics.
- Randrianjatovo-Gbalou, Irina; Rosario, Sandrine; Sismeiro, Odile; Varet, Hugo; Legendre, Rachel; Coppée, Jean-Yves; Huteau, Valérie; Pochet, Sylvie; Delarue, Marc . Enzymatic synthesis of random sequences of RNA and RNA analogues by DNA polymerase theta mutants for the generation of aptamer libraries.
- Potapov, Vladimir; Fu, Xiaoqing; Dai, Nan; Corrêa, Ivan R. Jr; Tanner, Nathan A.; Ong, Jennifer L. . Base modifications affecting RNA polymerase and reverse transcriptase fidelity.