5-Methyluridine-5'-Triphosphate

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N-1024
5-Methyl-UTP, 5-Me-UTP, 5-mUTP
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SKU Unit Size Price Qty
N-1024-1 1 µmole
$91.00
N-1024-5 5 µmole
$438.00
N-1024-10 10 µmole
$750.00
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Product Details

Catalog No N-1024
Purity ≥90% by AX-HPLC
Extinction Coefficient 9,650 Lmol-1cm-1 at 267 nm
Molecular Formula C10H17N2O15P3 (free acid)
Molecular Weight 498.10 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H2O
Recommended Storage -20°C or below
Other Name(s) 5-Methyl-UTP, 5-Me-UTP, 5-mUTP
Application Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Backbone 5'-Triphosphate
Base Analog(s) Thymidine, Uridine
Sugar Type(s) RNA
Nucleotide Category Base Modified RNA

Technical Documents




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References

Nguyen, Allen; Zhao, Connie; Dorris, David; Mazumder, Abhijit . Quantitative assessment of the use of modified nucleoside triphosphates in expression profiling: differential effects on signal intensities and impacts on expression ratios.

Karikó, Katalin; Muramatsu, Hiromi; Welsh, Frank A.; Ludwig, János; Kato, Hiroki; Akira, Shizuo; Weissman, Drew . Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability.

Karikó, Katalin; Buckstein, Michael; Ni, Houping; Weissman, Drew . Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA.

Anderson, Bart R.; Muramatsu, Hiromi; Nallagatla, Subba R.; Bevilacqua, Philip C.; Sansing, Lauren H.; Weissman, Drew; Karikó, Katalin . Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation.

Schein, Catherine H.; Oezguen, Numan; van der Heden van Noort, Gerbrand J.; Filippov, Dmitri V.; Paul, Aniko; Kumar, Eric; Braun, Werner . NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU).

Motorin, Yuri; Helm, Mark . RNA nucleotide methylation.

Lai, Zijuan; Tsugawa, Hiroshi; Wohlgemuth, Gert; Mehta, Sajjan; Mueller, Matthew; Zheng, Yuxuan; Ogiwara, Atsushi; Meissen, John; Showalter, Megan; Takeuchi, Kohei; Kind, Tobias; Beal, Peter; Arita, Masanori; Fiehn, Oliver . Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics.

Randrianjatovo-Gbalou, Irina; Rosario, Sandrine; Sismeiro, Odile; Varet, Hugo; Legendre, Rachel; Coppée, Jean-Yves; Huteau, Valérie; Pochet, Sylvie; Delarue, Marc . Enzymatic synthesis of random sequences of RNA and RNA analogues by DNA polymerase theta mutants for the generation of aptamer libraries.

Potapov, Vladimir; Fu, Xiaoqing; Dai, Nan; Corrêa, Ivan R. Jr; Tanner, Nathan A.; Ong, Jennifer L. . Base modifications affecting RNA polymerase and reverse transcriptase fidelity.