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Magnetic Beads & Agarose

Highest biotin-binding streptavidin magnetic beads and agarose available

Over the past 15 years, NanoLink™ and MagnaLink™ streptavidin-coupled Beads have been widely used in all types of organizations and are regularly cited in papers for diverse manual and automated applications. Watch the video to learn more:


TriLink offers streptavidin magnetic beads and agarose with the highest biotin-binding capacity on the market – beads with as much as 12X higher binding capacity and agarose with 20% lower price. Higher binding translates into reduced bead mass or agarose required to immobilize a biotinylated sample and lower background noise from nonspecific binding, resulting in better signals and lower net costs.

Molecule

NanoLink (1.0 um) Binding Capacity

MagnaLink (2.8 um) Binding Capacity

Free biotin
>14 nmol/mg
>12 nmol/mg
Biotinylated oligo (23-mer)
>2.5 nmol/mg
>0.8 nmol/mg
Biotinylated IgG (3 biotins per IgG)
>250 ug/mg
>112.6 ug/mg

The secret is in the crosslinking
The key to high biotin binding is in the unique covalently crosslinked streptavidin, based on Chromalink™ technology. The high surface area, when combined with our efficient linking chemistry, produces a consistent, ultra-high, biotin-binding bead.


Applications

  • Immobilization of biotinylated biomolecules or drugs
  • Immunoprecipitation, ChIP, cell capture, and others
  • Cell-surface labeling with biotinylation reagents, followed by precipitation with streptavidin
  • Recovery of biotinylated DNA for dideoxy sequencing

Streptavidin Agarose Ultra Performance


High biotin-binding streptavidin agarose


TriLink’s Streptavidin Agarose Ultra Performance™ provides high biotin binding at a low price. We use Chromalink™ technology. coupled with a 6% highly crosslinked agarose to boost the biotin binding capacity of the high specific activity streptavidin. This ideal combination provides a biotin binding capacity of >330 nmol/mL of resin—one of the highest loading-capacity products currently available. Use TriLink’s Streptavidin Agarose Ultra Performance™ for improved recovery of any biotinylated biomolecule and you can lower nonspecific binding, lower costs, and get better results.

Application Note: How to Capture at Least 2x More Antigen in an Immunoprecipitation

Comparative Binding Data

Advantages

  • High binding capacity - Higher biotin binding capacity at >20% lower price
  • Crosslinked agarose - TriLink's proprietary linker enables higher binding capacity, lower background, and less leaching
  • Multiple sizes - Available in 2 mL, 5 mL, 10 mL, and custom bulk packaging

Applications

  • Immobilization of biotinylated biomolecules or drugs
  • Immunoprecipitation, ChIP, cell capture, and others
  • Cell-surface labeling with biotinylation reagents, followed by precipitation with streptavidin
  • Recovery of biotinylated DNA for dideoxy sequencing

       
 

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