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Cloaking mRNA to Control Stability and Translation in Cells
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Cloaking mRNA to Control Stability and Translation in Cells

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Posted in: Nucleic Acids Therapeutics
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Perspectives on In Vitro Transcription (IVT) mRNA Sequence Optimization
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Perspectives on In Vitro Transcription (IVT) mRNA Sequence Optimization

This blog provides some perspective on published strategies for this type of sequence optimization, which is alternatively referred to sequence engineering. This topic has been trending upwards in recent years, as indicated by the linear forecast dashed line shown in this chart reports found by word searching the NIH PubMed database for 2013 – 2020.

Posted in: Nucleic Acids
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Aerosol Delivery of Naked mRNA – Part 2 

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Posted in: Nucleic Acids Therapeutics
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Sulfur-Modified Phosphorothioate Linkages in Bacterial DNA

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Posted in: Nucleic Acids
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Specificity Enhancement of PCR and Other DNA Polymerization Using Phosphorothioate-Modified dNTPs

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Posted in: Nucleic Acids Diagnostics
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Feasibility of Antisense Oligonucleotides as DNA Insecticides

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Posted in: Nucleic Acids RNA Interference (RNAi) Antisense
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New Chemical Ligations Compatible with Polymerase-Mediated Nucleic Acid Assembly 

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Posted in: Nucleic Acids Modified Oligos NGS
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Highlights from the 16th Annual Oligonucleotide Therapeutics Society (OTS) Meeting 

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Posted in: Nucleic Acids Modified Oligos RNA Interference (RNAi) Antisense Therapeutics
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Environmental DNA (eDNA) Applications—Recent Advances and Future Prospects

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Posted in: Nucleic Acids NGS Identification
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Bio-Recycling Plastic and New Bio-Packaging—Recent Advances Using Nucleic Acid-Based Tools

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