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Nucleic Acids

Cloaking mRNA to Control Stability and Translation in Cells

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Cloaking mRNA to Control Stability and Translation in Cells

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Perspectives on In Vitro Transcription (IVT) mRNA Sequence Optimization

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Perspectives on In Vitro Transcription (IVT) mRNA Sequence Optimization

This blog provides some perspective on published strategies for this type of sequence optimization, which is alternatively referred to sequence engineering. This topic has been trending upwards in recent years, as indicated by the linear forecast dashed line shown in this chart reports found by word searching the NIH PubMed database for 2013 – 2020.

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Aerosol Delivery of Naked mRNA – Part 2

Nanoparticles Delivery mRNA nucleic acids proteins Pseudouridine modified mRNA

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Sulfur-Modified Phosphorothioate Linkages in Bacterial DNA

DNA Structure bacteria microbes DNA nucleic acids proteins biochemistry microbiome

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Specificity Enhancement of PCR and Other DNA Polymerization Using Phosphorothioate-Modified dNTPs

PCR nucleic acids

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Feasibility of Antisense Oligonucleotides as DNA Insecticides

gene engineering PCR oligo synthesis RNA nucleic acids biochemistry antisense

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New Chemical Ligations Compatible with Polymerase-Mediated Nucleic Acid Assembly

Sanger Sequencing sequencing mRNA PCR oligo synthesis RNA nucleic acids

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Highlights from the 16th Annual Oligonucleotide Therapeutics Society (OTS) Meeting

PCR oligo synthesis RNA nucleic acids antisense Editing modified RNA

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Environmental DNA (eDNA) Applications—Recent Advances and Future Prospects

Nucleic Acid ancient DNA sequencing PCR nanopore sequencing bacteria microbes DNA nucleic acids microbiome

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Bio-Recycling Plastic and New Bio-Packaging—Recent Advances Using Nucleic Acid-Based Tools

sequencing gene engineering bacteria microbes DNA nucleic acids proteins biochemistry