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Nucleic Acids
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Perspectives on In Vitro Transcription (IVT) mRNA Sequence Optimization
This blog provides some perspective on published strategies for this type of sequence optimization, which is alternatively referred to sequence engineering. This topic has been trending upwards in recent years, as indicated by the linear forecast dashed line shown in this chart reports found by word searching the NIH PubMed database for 2013 – 2020.
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New Chemical Ligations Compatible with Polymerase-Mediated Nucleic Acid Assembly
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Highlights from the 16th Annual Oligonucleotide Therapeutics Society (OTS) Meeting
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