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Posts tagged 'modified RNA'

mRNA Therapeutics for Neurological Diseases and Pain
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mRNA Therapeutics for Neurological Diseases and Pain

Nanoparticles mRNA proteins modified RNA delivery
Posted in: Therapeutics
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Cloaking mRNA to Control Stability and Translation in Cells
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Cloaking mRNA to Control Stability and Translation in Cells

nucleic acids modified mRNA modified RNA nanoparticles
Posted in: Nucleic Acids Therapeutics
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Advances in Cancer CAR T-Cell Immunotherapy Using IVT-mRNA
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Advances in Cancer CAR T-Cell Immunotherapy Using IVT-mRNA

mRNA cancer proteins CRISPR modified mRNA modified RNA
Posted in: Therapeutics
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CleanCap® IVT Cas9 mRNA in Micelles Used for Genome Editing in Mouse Brain for the First Time
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CleanCap® IVT Cas9 mRNA in Micelles Used for Genome Editing in Mouse Brain for the First Time

Nanoparticles Delivery genome Editing CRISPR modified mRNA gene editing Editing modified RNA

CRISPR-based genome editing tools show tremendous potential as therapeutic agents for the treatment of genetic diseases and viral infections, as discussed in previous Zone blogs and the June 2021 TriLink Research Spotlight titled, A Novel Base-Editing Strategy Promises to Treat Sickle Cell Disease. Nevertheless, safe and efficient delivery of CRISPR tools to target tissues continues to attract growing attention (see Chart). A wide variety of technical approaches are being explored, the main one being the formulation of nano-sized particles loaded with different types of CRISPR-related cargo.

Posted in: Therapeutics
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Highlights from the 16th Annual Oligonucleotide Therapeutics Society (OTS) Meeting 

PCR oligo synthesis RNA nucleic acids antisense Editing modified RNA
Posted in: Nucleic Acids Modified Oligos RNA Interference (RNAi) Antisense Therapeutics
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Direct RNA Sequencing by Use of Nanopores

sequencing mRNA PCR nanopore sequencing microbes methylation RNA Pseudouridine modified mRNA modified RNA
Posted in: Epigenetics NGS
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The “Wuhan Virus” Outbreak—Molecular Aspects of Coronaviruses (CoV)

sequencing mRNA PCR microbes RNA modified mRNA diagnostics antisense modified RNA
Posted in: Nucleic Acids Diagnostics Therapeutics Identification
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Kool Chemistries for Modifying and Manipulating RNA

Unnatural Base Pairs nucleic acids CRISPR modified mRNA gene editing Editing modified RNA
Posted in: Nucleic Acids
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Post-Transcriptional Labeling of RNA Using Suzuki–Miyaura Cross-Coupling

mRNA oligo synthesis RNA nucleic acids modified RNA
Posted in: Modified Oligos
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Surge in Lyme Disease Cases Reported to U.S. Congress as a Serious Health Concern

sequencing mRNA PCR bacteria DNA RNA diagnostics modified RNA
Posted in: Diagnostics NGS Therapeutics
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