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You are at: All > Nucleotides > Nucleotides by Structural Class > Sugar Modified Nucleoside Triphosphates

N-1009
2'-Fluoro-2'-deoxyguanosine-5'-Triphosphate
2'-F-dGTP

2'-Fluoro-2'-deoxyguanosine-5'-Triphosphate

Extinction Coefficient: 13,600 Lmol-1cm-1 at 252 nm
Molecular Weight: 525.1 g/mol (free acid)
Molecular Formula: C10H15N5O13P3F (free acid)
Salt Form: Lithium
Purity Specification: ≥95% by AX-HPLC

Shipped at 100 mM in H2O. 
1 µmole: 10 µL
5 µmole: 50 µL
10 µmole: 100 µL


 
Certificate(s) of Analysis

 



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   1 µmole ($53.00)
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   5 x 10 µmoles ($1,137.00)
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Reference(s)
Lauridsen LH, Rothnagel JA, Veedu RN. Enzymatic recognition of 2'-modified ribonucleoside 5'-triphosphates: towards the evolution of versatile aptamers. Chembiochem. 2012 Jan 2;13(1):19-25.
Cozens C, Pinheiro VB, Vaisman A, Woodgate R, Holliger P. A short adaptive path from DNA to RNA polymerases. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8067-72.
Reif R, Haque F, Guo P. Fluorogenic RNA Nanoparticles for Monitoring RNA Folding and Degradation in Real Time in Living Cells. Nucleic Acid Ther. 2012 Oct 31. doi:10.1089/nat.2012.0380.
Kanwar JR, Roy K, Kanwar RK. Chimeric aptamers in cancer cell-targeted drug delivery. Crit Rev Biochem Mol Biol. 2011 Dec;46(6):459-77.
Rhie A, et al. Characterization of 2'-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion. (2003) J. Biol. Chem., 278: 39697-705.
Sun LQ, Cairns MJ, Saravolac EG, Baker A, Gerlach WL. Catalytic nucleic acids: From lab to application. (2000) Pharmacological Reviews, 52: 325-347.
Jayasena SD. Aptamers: An emerging class of molecules that rival antibodies in diagnostics. (1999) Clinical Chemistry, 45(9): 1628-1650.
Ono T, Scalf M, Smith LM. 2'-Fluoro modified nucleic acids: polymerase-directed synthesis, properties and stability to analysis by matrix-assisted laser desorption/ionization mass spectrometry. Nucleic Acids Res. 1997 Nov 15;25(22):4581-8.


 

 


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