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You are at: All > Nucleotides > Nucleotides by Structural Class > Sugar Modified Nucleoside Triphosphates

N-1015
2'-O-Methyladenosine-5'-Triphosphate
2'-O-Methyl-ATP

2'-O-Methyladenosine-5'-Triphosphate

Extinction Coefficient: 15,400 Lmol-1cm-1 at 258 nm
Molecular Weight: 521.2 g/mol (free acid)
Molecular Formula:  : C11H18N5O13P(free acid)
Salt Form: Lithium
Purity Specification: ≥95% by AX-HPLC 

Shipped at 100 mM in H2O.
1 µmole: 10 µL
5 µmole: 50 µL
10 µmole: 100 µL


 
Certificate(s) of Analysis
 



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   1 µmole ($32.00)
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Reference(s)
Zhang L, Wang J, Coetzer M, Angione S, Kantor R, Tripathi A.One-Step Ligation on RNA Amplification for the Detection of Point Mutations.J Mol Diagn. 2015 Nov;17
Meyer KD, Saletore Y, Zumbo P, Elemento O, Mason CE, Jaffrey SR. Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons. Cell. 2012. doi: 10.1016/j.cell.2012.05.003
Lauridsen LH, Rothnagel JA, Veedu RN. Enzymatic recognition of 2'-modified ribonucleoside 5'-triphosphates: towards the evolution of versatile aptamers. Chembiochem. 2012 Jan 2;13(1):19-25.
Kanwar JR, Roy K, Kanwar RK. Chimeric aptamers in cancer cell-targeted drug delivery. Crit Rev Biochem Mol Biol. 2011 Dec;46(6):459-77.
Xiao Z, et. al. Engineering of Targeted Nanoparticles for Cancer Therapy Using Internalizing Aptamers Isolated by Cell-Uptake Selection. ACS Nano. 2012 Jan 3. doi: 10.1021/nn204165v
Fa M, et al. Expanding the substrate repertoire of a DNA polymerase by directed evolution. (2004) JACS, 126(6): 1748-1754.
Cho HD, Oyelere AK, Strobel SA, Weiner AM. Use of nucleotide analogs by class I and class II CCA-adding enzymes (tRNA nucleotidyltransferase): deciphering the basis for nucleotide selection. (2003) RNA, 3(8): 970-81.
Vaish NK, et al. A novel, modification-dependent ATP-binding aptamer selected from an RNA library incorporating a cationic functionality. (2003) Biochemistry, 42: 8842-8851.
Missiaen L, Parys JB, Smedt HD, Sienaert I, Sipma H, Vanlingen S, Maes K, Casteels R. Effect of adenine nucleotides on myo-inositol-1,4,5-trisphosphate-induced calcium release. (1997) Biochem J., 325(Pt 3): 661-6.


 

 


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