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You are at: All > Nucleotides > Nucleotides by Structural Class > Sugar Modified Nucleoside Triphosphates

N-1017
2'-O-Methylguanosine-5'-Triphosphate
2'-O-Methyl-GTP

2'-O-Methylguanosine-5'-Triphosphate

Extinction Coefficient: 13,600 Lmol-1cm-1 at 252 nm
Molecular Weight: 537.2 g/mol (free acid)
Molecular Formula:  : C11H18N5O14P(free acid)
Salt Form: Lithium
Purity Specification: ≥90% by AX-HPLC 

Shipped at 100 mM in H2O.
1 µmole: 10 µL
5 µmole: 50 µL
10 µmole: 100 µL


 
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Reference(s)
Kanwar JR, Roy K, Kanwar RK. Chimeric aptamers in cancer cell-targeted drug delivery. Crit Rev Biochem Mol Biol. 2011 Dec;46(6):459-77.
Heck J, et al. Effects of Mutagenic and Chain-Terminating Nucleotide Analogs on Enzymes Isolated from Hepatitis C Virus Strains of Various Genotypes. Antimicrobial Agents and Chemotherapy.
Paeshuyse J, et al. The Imidazopyrrolopyridine Analogue AG110 Is a Novel, Highly Selective Inhibitor of Pestiviruses That Targets the Viral RNA-Dependent RNA Polymerase at a Hot Spot for Inhibition of Viral Replication, Journal of Virology.
Paeshuyse J, et al. A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase. (2006) Journal of Virology, 80(1): 149-160.
Dutartre H, Boretto J, Guillemot JC, Canard B. A relaxed discrimination of 2'-O-methyl-GTP relative to GTP between de novo and Elongative RNA synthesis by the hepatitis C RNA-dependent RNA polymerase NS5B. (2005) J. Biol. Chem., (280)(8): 6359-6368.


 

 


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