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You are at: All > Nucleotides > Nucleotides by Structural Class > Sugar Modified Nucleoside Triphosphates

N-1033
Aracytidine-5'-Triphosphate
1-β-D-arabinofuranosylcytosine TP, Ara-CTP

Aracytidine-5'-Triphosphate

Extinction Coefficient: 9,100 Lmol-1cm-1 at 271 nm
Molecular Weight: 483.1 g/mol (free acid)
Molecular Formula: C9H16N3O14P(free acid)
Salt Form: Lithium
Purity Specification: ≥90% by AX-HPLC 

Shipped at 100 mM in H2O.
1 µmole: 10 µL
5 µmole: 50 µL
10 µmole: 100 µL


 
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Reference(s)
Vaisman A, Wojciech K, McDonald JP, Karata K, Yang W, Goodman MF, Woodgate R. Critical amino acids in Escherichia coli UmuC responsible for sugar discrimination and base-substitution fidelity. Nucleic Acids Res. (2012), doi: 10.1093/nar/gks233.
Pinheiro VB, Taylor AI, Cozens C, Abramov M, Renders M, Zhang S, Chaput JC, Wengel J, Peak-Chew SY, McLaughlin SH, Herdewijn P, Holliger P. Synthetic genetic polymers capable of heredity and evolution. Science. 2012 Apr 20;336(6079):341-4.
Prakasha Gowda AS, Polizzi JM, Eckert KA, Spratt TE. Incorporation of gemcitabine and cytarabine into DNA by DNA polymerase beta and ligase III/XRCC1. (2010) Biochemistry, (49)(23): 4833-4840.
Brown JA, Fiala KA, Fowler JD, Sherrer SM, Newmister SA, Duym WW, Suo Z. A novel mechanism of sugar selection utilized by a human X-family DNA polymerase. (2010) J Mol Biol. 15;395(2):282-90.
Brown JA, Fowler JD, Suo Z. Kinetic basis of nucleotide selection employed by a protein template-dependent DNA polymerase. (2010) Biochemistry, (49)(26): 5504-5510
Skalski V, et. al. A 3'-5' exonuclease in human leukemia cells: implications for resistance to 1-beta -D-arabinofuranosylcytosine and 9-beta -D-arabinofuranosyl-2-fluoroadenine 5'-monophosphate. J Biol Chem. 2000 Aug 18;275(33):25814-9.


 

 


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