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You are at: All > Nucleotides > Nucleotides by Structural Class > Base Modified Deoxynucleoside Triphosphates

N-2026
5-Methyl-2'-deoxycytidine-5'-Triphosphate
5-Methyl-dCTP, m5-dCTP, 5-m-dCTP, 5m-dCTP

5-Methyl-2'-deoxycytidine-5'-Triphosphate

Extinction Coefficient: 8,900 Lmol-1cm-1 at 278 nm
Molecular Weight: 481.1 g/mol (free acid)
Molecular Formula: C10H18N3O13P3 (free acid)
Salt Form: Lithium
Purity Specification: ≥95% by AX-HPLC 

Shipped at 100 mM in H2O.
1 µmole: 10 µL
5 µmole: 50 µL
10 µmole: 100 µL


 
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Reference(s)
Xu A, Desai AM, Brenner SE, Kirsch JF. A Continuous Fluorescence Assay for the Characterization of Nudix Hydrolases. Anal Biochem. 2013 Mar 6. doi: 10.1016/j.ab.2013.02.023.
Mellén M, Ayata P, Dewell S, Kriaucionis S, Heintz N. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell. 2012 Dec 21;151(7):1417-30.
Portela A, Esteller M. Epigenetic modifications and human disease. (2010) Nature Biotechnology (28)10:1057-1068.
Schildberg F, Hagmann C, Bohnert V, Tolba R. Improved transplantation outcome by epigentic changes. (2010) Transplant Immunology 23:104-110.
Use of Base-Modified Duplex-Stabilizing Deoxynucleoside 5′-Triphosphates To Enhance the Hybridization Properties of Primers and Probes in Detection Kutyavin I. Use of Base-Modified Duplex-Stabilizing Deoxynucleoside 5' Triphosphates, Biochemistry 2008.
Suspène R, et al. Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs, Nucleic Acid Research.
Kamiya H, et al. Suppression of spontaneous and hydrogen peroxide-induced mutations by a MutT-type nucleotide pool sanitization enzyme, the Escherichia coli Orf135 protein. Genes Cells. 2003 Dec;8(12):941-50.
Wong KK, Markillie LM, Saffer JD. A novel method for producing partial restriction digestion of DNA fragments by PCR with 5-methyl-CTP. (1997) Nucleic Acids Res, 25(20): 4169-71.


 

 


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