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You are at: All > Nucleotides > Nucleotides by Structural Class > Base Modified Deoxynucleoside Triphosphates

N-2033
8-Oxo-2'-deoxyadenosine-5'-Triphosphate
8-Oxo-dATP

8-Oxo-2'-deoxyadenosine-5'-Triphosphate

Extinction Coefficient: 13,600 Lmol-1cm-1 at 267 nm
Molecular Weight: 507.1 g/mol (free acid)
Molecular Formula: C10H16N5O13P3 (free acid)
Salt Form: Lithium
Purity Specification: ≥90% by AX-HPLC 

Shipped at 100 mM in H2O.
1 µmole: 10 µL
5 µmole: 50 µL
10 µmole: 100 µL


 
Certificate(s) of Analysis
N-2033-112901-3



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Reference(s)
Devadoss B, Lee I, Berdis AJ. Enhancing the "A-rule" of translesion DNA synthesis: promutagenic DNA synthesis using modified nucleoside triphosphates. (2007) Biochemistry, (46)(48): 13752-13761.
Fujikawa K, Kamiya H, Yakushiji H, Fujii Y, Nakabeppu Y, Kasai H. The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein. (1999) J Biol Chem., 274(26): 18201-5.
Fujikawa K, Kamiya H, Kasai H. The mutations induced by oxidatively damaged nucleotides, 5-formyl-dUTP and 5-hydroxy-dCTP,in Escherichia coli. (1998) Nucleic Acids Res., 26(20): 4582-7.


 

 


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