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You are at: All > Nucleotides > Nucleotides by Structural Class > Sugar Modified Nucleoside Triphosphates

N-3002
3'-Deoxyguanosine-5'-Triphosphate
3'-dGTP

3'-Deoxyguanosine-5'-Triphosphate

Extinction Coefficient: 13,600 Lmol-1cm-1 at 252 nm
Molecular Weight: 507.1 g/mol (free acid)
Molecular Formula: C10H16N5O13P3 (free acid)
Salt Form: Lithium
Purity Specification: ≥95% by AX-HPLC 

Shipped at 100 mM in H2O.
1 µmole: 10 µL
5 µmole: 50 µL
10 µmole: 100 µL


 
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Reference(s)
Cabart P, Luse DS. Inactivated RNA Polymerase II Open Complexes Can Be Reactivated with TFIIE. J Biol Chem. 2012 Jan 6;287(2):961-7.
Niyomrattanakit, P., et. al. Fluorescence-Based Alkaline Phosphatase-Coupled Polymerase Assay for Identification of Inhibitors of Dengue Virus RNA-Dependent RNA Polyermase (2011) Journal of Biomolecular Screening, 16(2), 201-210.
Cabart P, Luse DS. Inactivated RNA polymerase II open complexes can be reactivated with TFIIE. J Biol Chem. 2012 Jan 6;287(2):961-7.
Yakhnin AV, Babitzke P. NusA-stimulated RNA polymerase pausing and termination participates in the Bacillus subtilis trp operon attenuation mechanism in vitro. (2010) PNAS 99(17):11067-11072.
Heck J, et al. Effects of Mutagenic and Chain-Terminating Nucleotide Analogs on Enzymes Isolated from Hepatitis C Virus Strains of Various Genotypes. Antimicrobial Agents and Chemotherapy.
Ni Z, et al. P-TEFb is Critical for the Maturation of RNA Polymerase II into Productive Elongation In Vivo, Molecular and Cellular Biology.
Paeshuyse J, et al. The Imidazopyrrolopyridine Analogue AG110 Is a Novel, Highly Selective Inhibitor of Pestiviruses That Targets the Viral RNA-Dependent RNA Polymerase at a Hot Spot for Inhibition of Viral Replication, Journal of Virology.
Paeshuyse J, et al. A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase. (2006) Journal of Virology, 80(1): 149-160.
Stano NM, et al. T7 lysozyme represses T7 RNA polymerase transcription by destabilizing the open complex during initiation. (2004) J. Biol. Chem., 279(16): 16136-16143.
Stano NM, Levin MK, Patel SS. The +2 NTP binding drives open complex formation in T7 RNA polymerase. (2002) J. Biol. Chem., 277(40): 37292-300.


 

 


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