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You are at: All > Nucleotides > Nucleotides by Structural Class > Sugar Modified Nucleoside Triphosphates



Extinction Coefficient:15,400 Lmol-1cm-1 at 258 nm
Molecular Weight: 516.2 g/mol (free acid)
Molecular Formula: C10H15N8O11P3(free acid)
Salt Form:Lithium
Purity Specification: ≥90% by AX-HPLC

Shipped at 100 mM in H2O.
1 µmole: 10 µL
5 µmole: 50 µL
10 µmole: 100 µL


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Herman BD, et. al. Substrate mimicry: HIV-1 reverse transcriptase recognizes 6 modified-3'-azido-2',3'-dideoxyguanosine-5'-triphosphates as adenosine analogs. (2011) Nucleic Acids Research. Nucleic Acids Res. 2012 Jan;40(1):381-90.
Marchand, B., White, K.L., Ly, J.K., Margot, N.A., Wang, R., McDermott, M., Miller, M.D., Gotte, M. Effects of the Translocation Status of Human Immunodeficiency Virus Type 1 Reverse Transcriptase on the Efficiency of Excision of Tenofivor (2007) Antimicr
Liu X, et al. 3'-Azido-2',3'-dideoxynucleoside 5'-triphosphates inhibit telomerase activity in vitro, and the corresponding nucleosides cause telomere shortening in human HL60 cells, Nucleic Acid Research.
Hanes J, Johnson K. A novel mechanism of selectivity against AZT by the human mitochondrial DNA polymerase, Nucleic Acid Research.
Parikh UM, et. al. In vitro activity of structurally diverse nucleoside analogs against human immunodeficiency virus type 1 with the K65R mutation in reverse transcriptase. Antimicrob Agents Chemother. 2005 Mar;49(3):1139-44.
Sluis-Cremer N, et. al. The 3'-Azido group is not the primary determinant of the 3'-Azido-3'-deoxythymidine (AZT) responsible for the excision of AZT-resistant HIV-1. J Biol Chem. 2005 Aug 12;280(32):29047-52.
Sperber SJ, Feibusch EL, Damiani A, Weinstein MP. In vitro activities of nucleoside analog antiviral agents against salmonellae. (1993) Antimicrobial Agents & Chemotherapy, 37(1): 106-10.
Thormar H, Balzarini J, Holy A, Jindrich J, Rosenberg I, Debyser Z, Desmyter J, De Clercq E. Inhibition of visna virus replication by 2',3'-dideoxynucleosides and acyclic nucleoside phosphonate analogs. Antimicrob Agents Chemother. 1993 Dec;37(12):2540-4.



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