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You are at: All > Nucleotides > Nucleotides by Structural Class > Sugar Modified Nucleoside Triphosphates

N-4014
3'-Azido-2',3'-dideoxycytidine-5'-Triphosphate
3'-Azido-ddCTP

3'-Azido-2',3'-dideoxycytidine-5'-Triphosphate

Extinction Coefficient: 9,100 Lmol-1cm-1 at 271 nm
Molecular Weight: 492.2 g/mol (free acid)
Molecular Formula: C9H15O12N6P3 (free acid)
Salt Form: Lithium
Purity Specification: ≥90% by AX-HPLC

Shipped at 10 mM in H2O.
1 µmole: 100 µL
5 µmole: 500 µL
10 µmole: 1,000 µL


MSDS

Certificate(s) of Analysis



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Reference(s)
Herman BD, et. al. Substrate mimicry: HIV-1 reverse transcriptase recognizes 6 modified-3'-azido-2',3'-dideoxyguanosine-5'-triphosphates as adenosine analogs. (2011) Nucleic Acids Research. Nucleic Acids Res. 2012 Jan;40(1):381-90.
Hanes J, Johnson K. A novel mechanism of selectivity against AZT by the human mitochondrial DNA polymerase, Nucleic Acid Research.
Sluis-Cremer N, et. al. The 3'-Azido group is not the primary determinant of the 3'-Azido-3'-deoxythymidine (AZT) responsible for the excision of AZT-resistant HIV-1. J Biol Chem. 2005 Aug 12;280(32):29047-52.


 

 


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