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You are at: All > Oligonucleotides > Custom Oligonucleotide Components > Custom Oligonucleotide Components by Type > Dimers & Trimers

Cis-Syn Thymidine Dimer


Cis-Syn Thymidine Dimer

Cis-syn thymidine dimers are used in DNA damage and repair research. One of the major causes of DNA damage is UV from sunlight that results in dimerization of adjacent pyrimidine bases, forming cyclobutane dimers (CPDs). The majority of CPDs are cis-syn cyclobutane thymidine dimers.

Oligonucleotide Modification Price
5.0 µmole $4436
10 µmole $6221
15 µmole $7665

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Devadoss B, Lee I, Berdis AJ. Spectroscopic analysis of polymerization and exonuclease proofreading by a high-fidelity DNA polymerase during translesion DNA synthesis. Biochim Biophys Acta. 2012 Aug 28. doi: 10.1016/j.bbapap.2012.08.019.
Sanders, L.H., Devadoss, B., Raja, G.V., O'Connor, J., Su, S., Wozniak, D.J., Hassett, D.J., Berdis, A.J., Sutton, M.D. Epistatic Roles for Pseudomonas aeruginosa MutS and DinB (DNA Pol IV) in Coping with Reactive Oxygen Species-Induced DNA Damage (2011)
Clark TA, Spittle KE, Turner SW, Korlach J. Direct Detection and Sequencing of Damaged DNA Bases. Genome Integr. 2011 Dec 20;2(1):10.



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