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You are at: All > Oligonucleotides > Custom Oligonucleotide Components > Custom Oligonucleotide Components by Type > Backbones (Purification Options & Expected Yields)

Phosphodiester RNA
PO RNA

Phosphodiester RNA

Per Base Pricing
5.0 µmole $40.00
10 µmole $52.50
15 µmole $65.00
 
Purification Method 5.0 µmole 10 µmole 15 µmole
AX-HPLC $275 $375 $425
RP-Cartridge N/A N/A N/A
PAGE $500 $750 $1000
PAGE followed by RP-HPLC $725 $1025 $1325


Expected Yields* OD260 units approx. mg

5.0 μmole scale 50-150 1.48 - 4.44
10 μmole scale 100-300 2.96 - 8.88
15 μmole scale 150-400 4.45 - 13.33

Minimum pricing requirements may apply. Please request a quote for exact pricing or contact us to speak with a customer service representative.
 
*Expected yields are estimates for PAGE purified (~90%) unmodified oligonucleotides. Yield and purity differences can be caused by many factors, such as sequence and length. If you require a specific yield, please let us know when you place your order or request a quote.
 
Lehman "I have been very pleased at the synthetic RNAs I have purchased from TriLink. While the overall yields have not been overwhelming for longer RNAs, I have seen these yields increase over the years, and I do get better yields from TriLink than other companies that I have used. I also have had good success with the chemically modified nucleotides that I have purchased from TriLink. I have seen TriLink be in business for a long time since their inception, and this persistence in a tough marketplace speaks to the quality of their products."

Niles Lehman Professor of Chemistry
Portland State University
 



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Reference(s)
Mulvey JJ, Feinberg EN, Alidori S, McDevitt MR, Heller DA, Scheinberg DA. Synthesis, pharmacokinetics, and biological use of lysine-modified single-walled carbon nanotubes. International Journal of Nanomedicine. 2014:9(1). 4245-4255.
Shapiro AB, Gao N, Hajec L, McKinney DC. Time-dependent, reversible, oxaborole inhibition of Escherichia coli leucyl-tRNA synthetase measured with a continuous fluorescence assay. Anal Biochem. 2012 Sep 10;431(1):48-53. doi: 10.1016/j.ab.2012.08.024
Haque F, Shu D, Shu Y, Shlyakhtenko LS, Rychahou PG, Evers BM, Guo P. Ultrastable synergistic tetravalent RNA nanoparticles for targeting to cancers. Nano Today. 2012 Aug;7(4):245-257.


 

 


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