CpG RNA Dinucleotide (5'-3')

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O-31007
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SKU Unit Size Price Qty
O-31007-05 5 OD₂₆₀
$111.00
O-31007-25 25 OD₂₆₀
$265.00
O-31007-100 100 OD₂₆₀
$816.00
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Description

5 OD260 (0.278 µmoles) 25 OD260 (1.39 µmoles) 100 OD260 (5.56µmoles) 

Product Details

Catalog No O-31007
Purity ≥95% by AX-HPLC
Extinction Coefficient 18,000 Lmol-1cm-1 at 260 nm
Molecular Formula C19H25N8O12P (free acid)
Molecular Weight 588.40 g/mole (free acid)
Salt Form Na+
Concentration -
Recommended Storage -20°C or below
Application In vitro Transcription
Backbone Phosphodiester
Base Analog(s) Cytidine, Guanosine
Nucleotide Category 5'-3' Dinucleotide

Technical Documents



Certificate of Analysis


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References

Honda, A.; Mizumoto, K.; Ishihama, A. . RNA polymerase of influenza virus. Dinucleotide-primed initiation of transcription at specific positions on viral RNA.

Samuels, M.; Fire, A.; Sharp, P. A. . Dinucleotide priming of transcription mediated by RNA polymerase II.

Krieg, A. M.; Yi, A. K.; Matson, S.; Waldschmidt, T. J.; Bishop, G. A.; Teasdale, R.; Koretzky, G. A.; Klinman, D. M. . CpG motifs in bacterial DNA trigger direct B-cell activation.

Stevanin, Mathias; Busso, Nathalie; Chobaz, Véronique; Pigni, Matteo; Ghassem-Zadeh, Sahar; Zhang, Li; Acha-Orbea, Hans; Ehirchiou, Driss . CD11b regulates the Treg/Th17 balance in murine arthritis via IL-6.

Durham, Nick M.; Holoweckyj, Nick; MacGill, Randall S.; McGlinchey, Kelly; Leow, Ching Ching; Robbins, Scott H. . GITR ligand fusion protein agonist enhances the tumor antigen-specific CD8 T-cell response and leads to long-lasting memory.

Voss, James E.; Macauley, Matthew S.; Rogers, Kenneth A.; Villinger, Francois; Duan, Lijie; Shang, Liang; Fink, Elizabeth A.; Andrabi, Raiees; Colantonio, Arnaud D.; Robinson, James E.; Johnson, R. Paul; Burton, Dennis R.; Haase, Ashley T. . Reproducing SIVΔnef vaccine correlates of protection: trimeric gp41 antibody concentrated at mucosal front lines.

Chen, Sam; Zaifman, Josh; Kulkarni, Jayesh A.; Zhigaltsev, Igor V.; Tam, Ying K.; Ciufolini, Marco A.; Tam, Yuen Yi C.; Cullis, Pieter R. . Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids.