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March eNews

Research Update

Tales of Aptamer Selection: Astute Observation and Thoughtful Experimentation or Serendipity?

While researchers enter an experiment looking for an aptamer targeted to a specific protein, in a recent report, From Ugly Duckling to Swan: Unexpected Identification from Cell-SELEX of an Anti-Annexin A2 Aptamer Targeting Tumors, Frédéric Ducongé and colleagues show that through careful observation and thoughtful experimentation even a failed round of selection can lead to the discovery of a disease-relevant aptamer.

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Case Study
Validation of Random Library for Aptamer Selection

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RNA Library for RNA Aptamer Selection
 
Latest Blog Post

DNA Day 2014

DNA Day is April 25 and commemorates the day in 1953 when James Watson, Francis Crick, Maurice Wilkins, Rosalind Franklin and colleagues published in Nature on the double-helix structure of DNA.

  • How’s the World Celebrating?
  • Zon's Top 3 “Likes” for 2014 DNA Day
  • Where’s the Love for RNA Day?

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DNA-Day-Offer
 
Aptamer Synthesis & Conjugation

aptamer-synthesis

TriLink offers custom synthesis of aptamers from tens of bases to tens of kilobases, due to our ability to do both chemical and templated enzymatic synthesis. Conjugation of a wide range of modifications, such as therapeutic payloads, transport molecules and labels to aptamers is also available. Learn More
 
New in 2014!

Previous Blog Post

Aptamers: Chemistry Bests Mother Nature’s Antibodies
  • Discovered ~20 years ago, aptamer applications are booming
  • aptamer
  • Modified oligos and nucleotide triphosphates play pivotal roles
  • World’s first chemical guided missile could be the answer to wiping out cancer
  • Are antibodies passé?

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