Using Small RNA Sequencing to Improve Diagnosis and Treatment of Coronary Artery Disease
Using next-generation sequencing (NGS) and CleanTag™ technology, French researchers discovered that a subclass of circulating small non-coding RNAs (sRNAs) is a biomarker for apoptotic lesional macrophages commonly associated with coronary artery disease (CAD). Currently, CAD lacks specific diagnostic criteria and is the leading cause of death worldwide. This discovery may enable a specific diagnostic avenue not previously available and aid in improving treatment through risk stratification.
"We are very close to predict, with just a blood withdrawal, if and when a heart attack may occur." - Dr. Emanuela Repetto.
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