Twitter Facebook Linked In Zone In Google Plus 
Research Update

Restoring Mitochondrial Health After Cellular Stress

Published last month in Cell, Harvard researchers reported that mitochondrial deacetylase, Sirtuin 3 (SIRT3), acts quickly and dynamically to reset acetylation through dissociation with ATP synthase. SIRT3 is known to target molecules that participate in oxidative metabolism, generating the electrons necessary for restoration of membrane potential. The authors hypothesize that this mechanism may act as a means to recover membrane potential after transient cellular stress, before relying upon mitophagy. This finding was identified through a comprehensive analysis of the mitochondrial sirtuin network, which is composed of SIRT3-5.

Sirtuins are a family of proteins that are perhaps most famous for their metabolic role promoting longevity. However, it is becoming more apparent that...


Read More
 
OligoBuilder®
Get instant pricing & ordering for oligos up to the 15 Ámole scale
Come and See Us
Precision Genome
Engineering
(Keystone)
January 8-12
Breckenridge, CO.
2017 Calendar
Last chance to reserve your 2017 TriLink Calendar before the New Year.
CleanTag™ Technology/PLOS ONE
Read the latest PLOS ONE journal article featuring CleanTag Technology and find out how to improve your sRNA Library Prep reads and eliminate adapter dimer formation.
CleanTag™ Small RNA Library Preparation Kits:
  • Increase mappable sequencing reads even with single cell level RNA inputs
  • Are optimized for samples with limited or compromised RNA
  • Enable automated high throughput analysis by eliminating PAGE purification
  • Provide high assay sensitivity and accuracy, resulting in unmatched data quality
  • Increase library prep throughput with complete process automation
  • Compatible with Illumina and Ion Torrent platforms
Learn More
 
Ask An Expert

What do you recommend to purify my library after using CleanTag™?

We recommend a two step magnetic bead purification using Agencourt AMPure® XP-PCR Purification (A63880) by Beckman Coulter. The protocol can be found on the product insert for the CleanTag™ Small RNA Library Prep Kit (Cat# L-3206).

Read More FAQ's
Zone In With Zon Blog Post

Nanobombs for Light-Activated MicroRNA Drug Delivery

Every once in a while the title of a publication grabs my attention so much that I just have to read it, and that's what happened when I read this one A Near-Infrared Laser-Activated "Nanobomb" for Breaking the Barriers to MicroRNA Delivery...

View Blog Post

 

 
 
© 2016 TriLink BioTechnologies | All Rights Reserved