5' Guanosine-triphosphate Cap

5' Gppp
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This modification is available as part of a custom oligonucleotide configuration. Please use OLIGObuilder™ to generate pricing and order or contact us to speak with a customer service representative.

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Product Details

OLIGObuilder Code {Gppp.}
Other Name(s) 5' Gppp
Design Requirements 5′ guanosine triphosphate oligos are not compatible with free amine modifications.
Oligo Modification Type 5' Terminal Caps (Capped Oligos)


References

Konarska, M. M.; Padgett, R. A.; Sharp, P. A. . Recognition of cap structure in splicing in vitro of mRNA precursors.

Lim, Siew Pheng; Sonntag, Louis Sebastian; Noble, Christian; Nilar, Shahul H.; Ng, Ru Hui; Zou, Gang; Monaghan, Paul; Chung, Ka Yan; Dong, Hongping; Liu, Boping; Bodenreider, Christophe; Lee, Gladys; Ding, Mei; Chan, Wai Ling; Wang, Gang; Jian, Yap Li; Chao, Alexander Theodore; Lescar, Julien; Yin, Zheng; Vedananda, T. R.; Keller, Thomas H.; Shi, Pei-Yong . Small molecule inhibitors that selectively block dengue virus methyltransferase.

Shatkin, A. J. . Capping of eucaryotic mRNAs.

Furuichi, Y.; LaFiandra, A.; Shatkin, A. J. . 5'-Terminal structure and mRNA stability.

Edery, I.; Sonenberg, N. . Cap-dependent RNA splicing in a HeLa nuclear extract.

Kozak, M. . Structural features in eukaryotic mRNAs that modulate the initiation of translation.

Murthy, K. G.; Park, P.; Manley, J. L. . A nuclear micrococcal-sensitive, ATP-dependent exoribonuclease degrades uncapped but not capped RNA substrates.

Izaurralde, E.; Stepinski, J.; Darzynkiewicz, E.; Mattaj, I. W. . A cap binding protein that may mediate nuclear export of RNA polymerase

Hatta, T.; Ishikawa, M.; Takai, K.; Nakada, S.; Yokota, T.; Hata, T.; Miura, K.; Takaku, H. . Inhibition of influenza virus RNA polymerase by 5'-capped short RNA fragments.

Tado, M.; Abe, T.; Hatta, T.; Ishikawa, M.; Nakada, S.; Yokota, T.; Takaku, H. . Inhibitory effect of modified 5'-capped short RNA fragments on influenza virus RNA polymerase gene expression.

Egloff, Marie-Pierre; Benarroch, Delphine; Selisko, Barbara; Romette, Jean-Louis; Canard, Bruno . An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization.

Hooker, Lisa; Sully, Rachel; Handa, Balraj; Ono, Naomi; Koyano, Hiroshi; Klumpp, Klaus . Quantitative analysis of influenza virus RNP interaction with RNA cap structures and comparison to human cap binding protein eIF4E.