N1-Methyl-2'-O-Methylpseudouridine-5'-Triphosphate

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N-1103
N1-Methyl-2'-O-Methylpseudo-UTP,N1,2'-O-Dimethylpseudo-UTP
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SKU Unit Size Price Qty
N-1103-1 1 µmole
$321.00
N-1103-5 5 µmole
$1,522.00
N-1103-10 10 µmole
$2,806.00
N-1103-50 5 x 10 µmole
$11,481.00
N-1103-100 10 x 10 µmole
$14,763.00
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Description

A modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase.  Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA.

Product Details

Catalog No N-1103
Purity ≥90% by AX-HPLC
Extinction Coefficient 8,800 Lmol-1cm-1 at 271 nm
Molecular Formula C11H19N2O15P3 (free acid)
Molecular Weight 512.10 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H2O
Recommended Storage -20°C or below
Other Name(s) N1-Methyl-2'-O-Methylpseudo-UTP,N1,2'-O-Dimethylpseudo-UTP
Application Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Backbone 5'-Triphosphate
Base Analog(s) Pseudouridine
Sugar Type(s) 2'-O-Methyl
Nucleotide Category Base Modified DNA

Technical Documents



Certificate of Analysis


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