N2-Methyl-2'-deoxyguanosine-5'-Triphosphate - (N-2028)
N2-Methyl-dGTP
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N-2028
Product details
Catalog No | N-2028 |
---|---|
Purity | ≥90% by AX-HPLC |
Extinction Coefficient | 14,800 Lmol-1cm-1 at 254 nm |
Molecular Formula | C11H18N5O13P3 (free acid) |
Molecular Weight | 521.20 g/mole (free acid) |
Salt Form | Li+ |
Concentration | 100 mM |
Buffer | H2O |
Recommended Storage | -20°C or below |
Other Name(s) | N2-Methyl-dGTP |
Application | Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies |
Backbone | 5'-Triphosphate |
Base Analog(s) | Guanosine |
Sugar Type(s) | DNA |
Nucleotide Category | Base Modified DNA |
Technical documents
N-2028 Safety Data Sheet
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Intellectual property
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References
- Devadoss, Babho; Lee, Irene; Berdis, Anthony J. . Enhancing the "A-rule" of translesion DNA synthesis: promutagenic DNA synthesis using modified nucleoside triphosphates.
- Zhang, Xuemei; Motea, Edward; Lee, Irene; Berdis, Anthony J. . Replication of a Universal Nucleobase Provides Unique Insight into the Role of Entropy during DNA Polymerization and Pyrophosphorolysis
- Reineks, Edmunds Z.; Berdis, Anthony J. . Evaluating the contribution of base stacking during translesion DNA replication.
- Dasari, Anvesh; Deodhar, Tejal; Berdis, Anthony J. . A Comparative Analysis of Translesion DNA Synthesis Catalyzed by a High-Fidelity DNA Polymerase.
- Jemth, Ann-Sofie; Gustafsson, Robert; Bräutigam, Lars; Henriksson, Linda; Vallin, Karl S. A.; Sarno, Antonio; Almlöf, Ingrid; Homan, Evert; Rasti, Azita; Warpman Berglund, Ulrika; Stenmark, Pål; Helleday, Thomas . MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP.