|Purity||≥90% by AX-HPLC|
|Extinction Coefficient||15,567 Lmol-1cm-1 at 265 nm|
|Molecular Formula||C11H18N5O13P3 (free acid)|
|Molecular Weight||521.20 g/mole (free acid)|
|Recommended Storage||-20°C or below|
|Other Name(s)||N6-Methyl-ATP, m6ATP|
|Application||Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies|
|Nucleotide Category||Base Modified RNA|
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Karikó, Katalin; Muramatsu, Hiromi; Welsh, Frank A.; Ludwig, János; Kato, Hiroki; Akira, Shizuo; Weissman, Drew . Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability.
Anderson, Bart R.; Muramatsu, Hiromi; Nallagatla, Subba R.; Bevilacqua, Philip C.; Sansing, Lauren H.; Weissman, Drew; Karikó, Katalin . Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation.
Anderson, Bart R.; Muramatsu, Hiromi; Jha, Babal K.; Silverman, Robert H.; Weissman, Drew; Karikó, Katalin . Nucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase L.
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Lee, JH;Wang, R;Xiong, F;Krakowiak, J;Liao, Z;Nguyen, PT;Moroz-Omori, EV;Shao, J;Zhu, X;Bolt, MJ;Wu, H;Singh, PK;Bi, M;Shi, CJ;Jamal, N;Li, G;Mistry, R;Jung, SY;Tsai, KL;Ferreon, JC;Stossi, F;Caflisch, A;Liu, Z;Mancini, MA;Li, W; . Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation
Kim, K;van Galen, P;Hovestadt, V;Rahme, G;Andreishcheva, E;Shinde, A;Gaskell, E;Jones, D;Shema, E;Bernstein, B; . Systematic detection of m6A-modified transcripts at single-molecule and single-cell resolution