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Oligonucleotides

DNA Oligos
RNA Oligos
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Specialty Oligos
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Oligos for IVD & Molecular Dx
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Mid-Scale Synthesis
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FAQs


  Mid-Scale Synthesis TriLink specializes in mid-scale synthesis (50 mg to multiple grams) of both DNA and RNA oligonucleotides. Our mid-scale oligos are available with phosphodiester (PO), phosphorothioate (PS) or PO/PS combination backbones. We offer an extensive selection of modifications for oligonucleotides such as linkers, spacers, dyes and modified bases. We can do mid-scale synthesis for almost any modification you may need. If you’re looking for mid-scale oligos with modifications, please submit a quote request and one of our specialists will contact you within 24 hours.

Our standard mid-scale oligo syntheses range from 50 milligrams to multiple grams, are typically purified by HPLC and analyzed by PAGE, HPLC and mass spectroscopy. Process development, cGMP/QSR manufacturing and unpurified, desalted-only oligos are also available. If you require more than 1 gram of material, modifications, additional processing and handling services, and/or a quantity that is not list below, please contact us for a custom quote.

Orders for unmodified DNA mid-scale oligos may be placed online (see quantity and pricing below). Purity and yield for mid-scale RNA oligonucleotides are highly dependent on sequence, therefore set pricing is not available. Please request a quotation for your RNA oligo(s) and one of our specialists will contact you within 24 hours.

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Pricing for Mid-Scale DNA Oligonucleotides

Prices listed are for unmodified oligonucleotides between 15 and 25 bases with a PO, PS or PO/PS backbone. The price includes HPLC purification and diafiltration.

Unusual sequence compositions may affect pricing. If you have an unusual sequence composition, such as a poly-G stretch or one causing secondary structure formation, one of our specialists will contact you with final pricing before processing your order.

 

HPLC Purified DNA Pricing
(Length: 15-25 bases, Backbone: PO, PS or PO/PS)

Quantity Price*
50 mg
$1,435
100 mg
$1,875
250 mg
$2,425
500 mg
$3,310
1.0 gram
$5,040
*Prices may vary due to sequence composition.


 

 

 

 
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