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mRNA CDMO services

Streamline your start with high-quality plasmid DNA

Plasmid DNA, used as an in vitro transcription template, is a critical starting material for mRNA manufacturing programs. To shorten timelines and simplify supply chains, integrate phase-appropriate, high-quality plasmid DNA templates into your mRNA manufacturing process with TriLink’s plasmid DNA-to-mRNA pathway, designed and optimized to support clinical mRNA therapeutic and vaccine programs.


Plasmid DNA-to-mRNA pathway advantages


Phase-appropriate, high-quality plasmid

Obtain the preferred DNA template for in vitro transcription with a phase-appropriate plasmid suitable for GMP mRNA manufacturing.


Streamlined process and timelines

Using a single partner for plasmid and mRNA production increases process efficiency and decreases lead time.


Expert support for each project

A dedicated team of plasmid and mRNA production experts will be assigned to your project for support at every step.

Plasmid production process optimized for mRNA applications

Optimal plasmid production yields a high-quality DNA template for in vitro transcription. The quality of plasmid DNA is influenced by many factors throughout the production process. At TriLink, each plasmid DNA production program is supported by a team of plasmid and mRNA production experts, providing guidance in program management, process development, analytical services, quality, and manufacturing.


Plasmid manufacturing capabilities and analytics purpose-built for mRNA


Our plasmid manufacturing suites are co-located at our San Diego facility with our mRNA manufacturing facilities. We utilize automated platforms from fermentation through purification.


We leverage comprehensive quality systems to deliver high-quality plasmid consistently and predictably. The fermenter capacity and scale are customizable and tailored to each program.


Comprehensive analytical testing and quality control (QC) assays are performed to ensure the plasmid DNA template is optimal for downstream mRNA manufacturing. Our in-house analytics team has over 20 years of experience developing, qualifying, validating, and performing analytical methods.

Get started today!

Contact our team of experts to discuss your plasmid and clinical mRNA manufacturing needs.

Inquire about Plasmid Manufacturing

Inquire about Plasmid Manufacturing

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Learn About Our Leading Production Facilities

Our facilities feature quality instrumentation with built-in cGMP compliance measures to support your next big breakthrough.


Plasmid Manufacturing Brochure Download


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