Phosphorothioates

PS, S-Oligo, Phosphorothioate Oligonucleotide, Thioate
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This modification is available as part of a custom oligonucleotide configuration. Please use OLIGObuilder™ to generate pricing and order or contact us to speak with a customer service representative.

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Product Details

OLIGObuilder Code (ps), *
Other Name(s) PS, S-Oligo, Phosphorothioate Oligonucleotide, Thioate
Application Antisense/RNAi, Aptamers, CRISPR
Property Nuclease Stability
Oligo Modification Type Backbone


References

Awasthi, Sita; Lubinski, John M.; Shaw, Carolyn E.; Barrett, Shana M.; Cai, Michael; Wang, Fushan; Betts, Michael; Kingsley, Susan; Distefano, Daniel J.; Balliet, John W.; Flynn, Jessica A.; Casimiro, Danilo R.; Bryan, Janine T.; Friedman, Harvey M. . Immunization with a vaccine combining herpes simplex virus 2 (HSV-2) glycoprotein C (gC) and gD subunits improves the protection of dorsal root ganglia in mice and reduces the frequency of recurrent vaginal shedding of HSV-2 DNA in guinea pigs compared to immunization with gD alone.

Freed, Daniel C.; Towne, Victoria M.; Casimiro, Danilo R.; Zhao, Qinjian; Fu, Tong-Ming . Evaluating functional antibodies in rhesus monkeys immunized with hepatitis B virus surface antigen vaccine with novel adjuvant formulations.

Kogut, Michael H.; He, Haiqi; Genovese, Kenneth J. . Bacterial toll-like receptor agonists induce sequential NF-κB-mediated leukotriene B4 and prostaglandin E2 production in chicken heterophils.

Kwissa, Marcin; Nakaya, Helder I.; Oluoch, Herold; Pulendran, Bali . Distinct TLR adjuvants differentially stimulate systemic and local innate immune responses in nonhuman primates.

Schettini, Jorge; Kidiyoor, Amritha; Besmer, Dahlia M.; Tinder, Teresa L.; Roy, Lopamudra Das; Lustgarten, Joseph; Gendler, Sandra J.; Mukherjee, Pinku . Intratumoral delivery of CpG-conjugated anti-MUC1 antibody enhances NK cell anti-tumor activity.

Tapia-Abellán, Ana; Martínez-Esparza, María; Ruiz-Alcaraz, Antonio J.; Hernández-Caselles, Trinidad; Martínez-Pascual, Cristina; Miras-López, Manuel; Such, José; Francés, Rubén; García-Peñarrubia, Pilar . The peritoneal macrophage inflammatory profile in cirrhosis depends on the alcoholic or hepatitis C viral etiology and is related to ERK phosphorylation.

Sun, Yan; Zhang, Ziwei; Grigoryants, Vladimir M.; Myers, William K.; Liu, Fei; Earle, Keith A.; Freed, Jack H.; Scholes, Charles P. . The internal dynamics of mini c TAR DNA probed by electron paramagnetic resonance of nitroxide spin-labels at the lower stem, the loop, and the bulge.

Hayashi, Tomoko; Yao, Shiyin; Crain, Brian; Chan, Michael; Tawatao, Rommel I.; Gray, Christine; Vuong, Linda; Lao, Fitzgerald; Cottam, Howard B.; Carson, Dennis A.; Corr, Maripat . Treatment of autoimmune inflammation by a TLR7 ligand regulating the innate immune system.

Hayashi, T.; Rao, S. P.; Takabayashi, K.; Van Uden, J. H.; Kornbluth, R. S.; Baird, S. M.; Taylor, M. W.; Carson, D. A.; Catanzaro, A.; Raz, E. . Enhancement of innate immunity against Mycobacterium avium infection by immunostimulatory DNA is mediated by indoleamine 2,3-dioxygenase.

Cecco, Loris De; Berardi, Martina; Sommariva, Michele; Cataldo, Alessandra; Canevari, Silvana; Mezzanzanica, Delia; Iorio, Marilena V.; Tagliabue, Elda; Balsari, Andrea . Increased Sensitivity to Chemotherapy Induced by CpG-ODN Treatment Is Mediated by microRNA Modulation

Dunand-Sauthier, Isabelle; Irla, Magali; Carnesecchi, Stéphanie; Seguín-Estévez, Queralt; Vejnar, Charles E.; Zdobnov, Evgeny M.; Santiago-Raber, Marie-Laure; Reith, Walter . Repression of arginase-2 expression in dendritic cells by microRNA-155 is critical for promoting T cell proliferation.

Lande, Roberto; Chamilos, Georgios; Ganguly, Dipyaman; Demaria, Olivier; Frasca, Loredana; Durr, Sophie; Conrad, Curdin; Schröder, Jens; Gilliet, Michel . Cationic antimicrobial peptides in psoriatic skin cooperate to break innate tolerance to self-DNA.

Sun, Yan; Borbat, Peter P.; Grigoryants, Vladimir M.; Myers, William K.; Freed, Jack H.; Scholes, Charles P. . Pulse dipolar ESR of doubly labeled mini TAR DNA and its annealing to mini TAR RNA.