S-SS-4FB Cleavable Crosslinker

SKU Unit Size Price Qty
S-1037-010 10 mg


S-SS-4FB is an analog of S-4FB with a cleavable disulfide group in the linker enabling intracellular cleavage of the conjugate. S-SS-4FB reacts with primary amines on proteins (through lysine amino acids), amino-modified oligonucleotides or surfaces, introducing a 4FB (4-formylbenzamide) linker that forms stable covalent conjugates with biomolecules containing HyNic linkers. Intracellularly, disulfide bonds of S-SS-4FB are cleaved by glutathione, liberating a drug payload from its carrier.

Product Details

Catalog No S-1037
Label/Modifier Type 4FB
Reactivity HyNic
Recommended Storage None
Application Antibody Labeling, Antisense/RNAi, Aptamers, Immunotherapeutics

Certificate of Analysis

Intellectual Property

SoluLINK Bioconjugation For Research Use Only. Not for use in diagnostic procedures. For additional licensing restrictions, please see the license agreement at trilinkbiotech.com/solulink-research-license.

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