Search results for: 'cas9 DNA'

The discovery of the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas system has revolutionized the field of molecular biology and medicine (reviewed by Kantor et al. ) . CRISPR-mediated genome editing initially involved the generation of a Cas9-induced double-strand DNA  repaired by either non-homologous end joining (NHEJ) mechanisms, or by homology-directed repair (HDR). The discovery of the clustered regularly interspaced short palindromic repeats (CRISP...