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Gene Replacement mRNA

Gene replacement is a popular application for mRNA. Many proteins cannot be replaced by exogenous protein delivery, for example, if they are intracellular, membrane bound, or post translationally modified or processed. Intracellular expression from mRNA dramatically expands the number of indications that could potentially be treated by protein replacement. Human erythropoietin (EPO) protein is a secreted protein that is easily measured in serum by enzyme-linked immunosorbent assay. EPO stimulates red blood cell creation, which can be measured using a hematocrit assay. EPO mRNA is available to model your secreted protein.

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10% OFF Reporter and Replacement Gene mRNA. Stock up on catalog reporter or replacement gene mRNA and save!

The code STOCKUP is applicable for up to 10% off your purchase of selected catalog numbers (L-7202-5, L-7201-5, L-7602-5, L-7601-5, L-7203-5, L-7204-5, L-7608-5, L-7208-5, L-7209-05) only from October 11, 2023 to December 15, 2023, 11:59 pm PST with code STOCKUP through our website. This does not include custom orders.This promotion is open to customers who do not qualify as distributors of TriLink BioTechnologies. Offer excludes bulk quotes. Discount applies to list price in effect at the time order is received by TriLink BioTechnologies. Offer cannot be applied to previous purchases and cannot be combined with other discounts or promotions (including established discounts, supply agreements, etc.). Offer void where prohibited, licensed or restricted by federal, state, provincial, or local laws, regulations, or agency/institutional policies. Other restrictions may apply. Terms are subject to change.