Custom Oligos

For over 20 years, TriLink has been an industry leader in synthesizing high quality oligonucleotides for research, diagnostics, therapeutics, and OEM. We offer a wide selection of DNA, RNA, modified, and specialty oligonucleotides in scales up to multiple grams. We are known throughout the world for our ability to successfully synthesize difficult and unusual constructs. 

Our commitment to offering unmatched quality is coupled with a dedication to providing the best customer service and technical support in the industry. When you partner with TriLink as your trusted supplier, you will maximize your budget and resources with our expertise in designing and synthesizing difficult constructs, experience our remarkably high success rates synthesizing complex oligos, and unparalleled purity and performance. 

We have been collaborating with customers at the forefront of scientific discovery to enable everything from exploration to commercialization. In support of cutting edge nucleic acid development, TriLink offers specialty oligos, including randomers, molecular beacons, UsiRNA, and TINA modifided oligos. 

In addition to custom oligo synthesis, we have an extensive OEM program that includes research and diagnostic grade GMP manufacturing. We work with many leading companies in the life science and pharmaceutical industries, such as Life Technologies and GenMark. Our expertise, combined with an extensive selection of modifications and conjugates, offers virtually endless possibilities for your oligonucleotide synthesis. Whether you need standard DNA and RNA oligos, or you're working with difficult and highly-modified sequences, we can synthesize at the scale and level of purity you require.

If you’re looking for oligos at scales up to 15 µmol, you can obtain pricing and submit an order through the TriLink OligoBuilder, our secure online oligonucleotide design and ordering system. For large-scale orders or for special purity, yield, or formulation of your oligo, please contact us and we will be happy to discuss your project needs.


Explore Our Custom Oligos

Custom DNA Oligos

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We offer a full range of DNA oligos at the scale and purity you need. From basic to complicated sequences and modifications, customization is available to produce any scale up to multiple grams.

Custom DNA Oligos

Custom RNA Oligos

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Antisense therapeutics, oligonucleotide based RNAi, microRNA mimics, and inhibitors are showing great promise as powerful research tools and new class of potential therapeutics. Find out more on how partnering with TriLink for RNA oligonucleutides can fuel your research.

Custom RNA Oligos

Mid and Large Scale Oligo Synthesis

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TriLink specializes in mid-scale and large-scale synthesis (50 mg to multiple grams) of both DNA and RNA oligonucleotides.

Mid and Large Scale Oligo Synthesis