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Upcoming events

World Vaccine Congress 2024

Venue: Walter E. Washington Convention Center, Washington DC
Date: Apr 01, 2024 - Apr 04, 2024
The World Vaccine Congress is the largest, most established meeting dedicated to vaccines.From basic research to commercial manufacture, this one meeting covers the whole vaccine value chain where science, government and manufacturers all come together to create groundbreaking progress.

You can find us at booth #509. Please feel free to schedule a meeting with us using the button below.

Round Table
Date: April 2, 2024
Time:11:40 AM ET & 12;30 PM ET
Title: Next-Generation mRNA Developments: Anticipated Tools and Trends in the Next Five Years

Featured Moderator:
Chanfeng Zhao, Ph.D.
Vice President of Chemistry and R&D, TriLink BioTechnologies

Featured Presentation
Date: April 3, 2023
Time: 12:10 PM ET
Title: Advancements in mRNA Capping Technology for Vaccine Development

Featured Speaker:
Chunping Xu, Ph.D.
Senior Director of Chemistry and R&D, TriLink BioTechnologies

Abstract:
he emergence of mRNA as a versatile platform for vaccine development holds immense promise beyond COVID-19. An essential part of any mRNA vaccine is the 5’ cap structure, which is critical to the stability and expression of an mRNA. In this presentation, we explore the impact of 5’ cap on the functions and properties of mRNA and provide an overview of the latest developments in mRNA capping technology. By understanding the critical attributes of 5' cap structures and employing innovative capping strategies, mRNA drug developers can enhance manufacturing efficiency, reduce costs, and streamline the manufacturing process of mRNA-based medicines—thereby accelerating the development of novel mRNA-based vaccines and offering new hope for patients worldwide.

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TIDES USA 2024

Venue: Hynes Convention Center, Boston, USA
Date: May 14, 2024 - May 17, 2024
Each year, the TIDES conference scientific agenda includes 150+ of the industry's top scientists to present the latest science and industry updates across the entire spectrum from discovery, preclinical, clinical development through CMC, Manufacturing and commercialization of therapeutics and vaccines for oligos, peptides, mRNA and genome editing products.

You can find TriLink at booth #TBD.

Featured Presentation
Date: May 15, 2024
Time: 12:35 PM ET
Title: Investigating Critical Quality Attributes of Cap2 mRNA Using Cap Analog Libraries

Featured Speaker:
Chunping Xu, PhD
Director of Chemistry and R&D, TriLink BioTechnologies

Summary: mRNA caps are involved in modulating translation initiation, mRNA stability, and self/non-self-recognition of mRNAs by the immune system. Cap 0 is not abundant in higher eukaryotes and can trigger innate immune responses. Cap 1 is found in all eukaryotes and promotes mRNA translation. Cap2 is present in 50% of eukaryrotic mRNA in nature and is believed to be a dynamic marker for mRNA aging. Also, cap2 functions to reduce activation of the innate immune response. In this presentation, we will discuss the results of screening cap 2 analogs for their impacts on protein expression and immunogenicity in mice..

Schedule a meeting with us

Register Now