Contact Us


Located in the San Diego biotech hub of Sorrento Valley, TriLink’s custom-built 105,000 sq. ft. facility features over 50,000 sq. ft. of manufacturing space. The facility was designed with flexibility and expansion in mind. Manufacturing space is divided across purpose-built suites, and individual floorplans can be modified to suit program needs. Our current configuration supports process development, oligonucleotide synthesis, custom mRNA synthesis, cGMP manufacturing, and more. The building’s large footprint and customizable nature enable continued expansion of our capabilities and production scale.

TriLink Headquarters Expansion

Construction is underway on two facility expansions, allowing us to add custom plasmid DNA manufacturing as part of our complete mRNA solutions. Contact us for more details on plasmid services and availability. Additional cGMP suites to support CleanCap® mRNA capping production will be completed in early 2021.


Oligo Synthesis

This lab features a variety of oligonucleotide synthesizer platforms, providing the flexibility to scale production from 1.0 µmol to 2.4 mmol. Other functions include chemical conversions, 5’ triphosphorylation, chemical capping, and conjugation of labels and dyes.



The chemistry lab is responsible for phosphorylation chemistry supporting our NTP production and custom synthesis programs. Work performed here is primarily organic synthesis, and involves high throughput solvent handling and purification.



Our mRNA space includes the process development and production activities that support our mRNA programs. Work performed here includes manufacturing from microgram through multi-gram scales, optimizing existing processes, and developing new industry-leading mRNA technologies.



Our cGMP manufacturing space is divided across independent suites in ISO Class 8 rooms and ISO Class 7 rooms. Each cGMP suite features its own airlock entrance, HEPA filtered single pass air, environmental monitoring, and ISO Class 5 spaces for final filtration and aliquoting.



The pilot plant enables TriLink to scale our manufacturing processes and support growing client demand.