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Resources

Title Speaker Location/Event Duration
CGMP
The Path to GMP Production: Video 8 of 8 from the TIDES 2018 workshop series by Dr. Anton McCaffrey Video Dr. Anton McCaffrey TIDES 2018 0:05:59
DELIVERY
Advantages of In vivo DNA Barcoding in Nanoparticle Selection: Quantifying how thousands of nanoparticles deliver nucleic acids in vivo using DNA barcodes. Video Dr. James Dahlman, Georgia Tech TIDES 2018 0:26:21
MRNA
mRNA Biology: Video 3 of 8 from the TIDES 2018 Workshop featuring Dr. Anton McCaffrey. Includes biology of mRNA location and sensor recognition. Video Dr. Anton McCaffrey TIDES 2018 0:02:27
mRNA Capping: Video 5 of 8 from the TIDES 2018 Workshop featuring Dr. Anton McCaffrey. m6Am, Cap 0, Cap 1, and Cap 2 explained in this summary of endogenous cap structures. Video Dr. Anton McCaffrey TIDES 2018 0:05:24
mRNA Applications: Summarizing mRNA applications that include genome engineering, gene replacement, and immunobiology. Video Dr. Anton McCaffrey TIDES 2018 0:03:35
Manufacturing Design Considerations: Video 4 of 8 from the TIDES 2018 Workshop featuring Dr. Anton McCaffrey. Includes: planning the optimal mRNA, mRNA synthesis, mRNA manufacturing processes, research phase, plasmid template, and poly A polymerase. Video Dr. Anton McCaffrey TIDES 2018 0:06:03
Why Use mRNA: Video 1 of 8 from the TIDES 2018 Workshop by Dr. Anton McCaffrey. Video Dr. Anton McCaffrey TIDES 2018 0:01:17
Design & Manufacturing of Chemically Modified mRNA Therapeutics: Design and Manufacturing of Chemically Modified Messenger RNA Therapeutics - Entire Video TIDES 2018 Workshop by Dr. Anton McCaffrey Video Dr. Anton McCaffrey TIDES 2018 1:00:56
Chemical Modification of mRNA: Part 7 of 8 of the TIDES 2018 workshop series by Dr. Anton McCaffrey. Includes topics surrounding modified RNA sequence space, sequence engineering, uridine depletion, purification methods, effect of cap structures, and var Video Dr. Anton McCaffrey TIDES 2018 0:21:45
In Vitro mRNA Capping: Video 6 of 8 TIDES 2018 featuring Dr. Anton McCaffrey discussing mRNA capping methods, capping characteristics, ARCA, CleanCap, and comparison data. Video Dr. Anton McCaffrey TIDES 2018 0:09:00