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Aptamers

Systematic Evolution of Ligands by Exponential Enrichment (SELEX) is used to identify nucleic acids with high affinities and specificities to a distinct target ligand. Frequent targets include small molecules, proteins/peptides, and carbohydrates. Aptamers frequently possess 2’-fluoro, 2’-O-methyl, phosphorothioates or 5-[(3-Indolyl)propionamide-N-allyl]-2'-deoxyuridine.

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