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2'-O-Methyladenosine-5'-Triphosphate - (N-1015)

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2'-O-Methyladenosine-5'-Triphosphate is an ATP analog which is methylated at the 2'-O position of the ribose sugar. Methylation at this position results in increased stability of the resulting RNA strand against base hydrolysis and nuclease cleavage. This makes it a useful NTP for aptamer synthesis where increased variation in nucleotide composition along with increased nuclease resistance are desired. 

Product details
Catalog No N-1015
Purity ≥95% by AX-HPLC
Extinction Coefficient 15,400 Lmol-1cm-1 at 258 nm
Molecular Formula C11H18N5O13P3 (free acid)
Molecular Weight 521.20 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H2O
Recommended Storage -20°C or below
Other Name(s) 2'-O-Methyl-ATP
Application Aptamers, Epigenetics/DNA Damage
Backbone 5'-Triphosphate
Base Analog(s) Adenosine
Sugar Type(s) 2'-O-Methyl
Nucleotide Category Sugar Modified
Technical documents

N-1015 Safety Data Sheet

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