3'-Azido-2',3'-dideoxythymidine-5'-Triphosphate - (N-4009)

3'-Azido-ddTTP, AZTTP, AZT-TP, Zidovudine Triphosphate, Azidothymidine Triphosphate

This product is now available upon request as a custom synthesis. It is not maintained as a stocked item.

Product Details

Catalog No N-4009
Purity ≥98% by AX-HPLC
Extinction Coefficient 9,650 Lmol-1cm-1 at 267 nm
Molecular Formula C10H16N5O13P3 (free acid)
Molecular Weight 507.10 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H2O
Recommended Storage -20°C or below
Other Name(s) 3'-Azido-ddTTP, AZTTP, AZT-TP, Zidovudine Triphosphate, Azidothymidine Triphosphate
Application Aptamers
Backbone 5'-Triphosphate
Base Analog(s) Thymidine
Nucleotide Category Sugar Modified

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References

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Brehm, Jessica H.; Scott, Yanille; Koontz, Dianna L.; Perry, Steven; Hammer, Scott; Katzenstein, David; Mellors, John W.; Sluis-Cremer, Nicolas . Zidovudine (AZT) monotherapy selects for the A360V mutation in the connection domain of HIV-1 reverse transcriptase.

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Álvarez, Mar; Nevot, María; Mendieta, Jesús; Martínez, Miguel A.; Menéndez-Arias, Luis . Amino acid residues in HIV-2 reverse transcriptase that restrict the development of nucleoside analogue resistance through the excision pathway.

Shock, David D.; Freudenthal, Bret D.; Beard, William A.; Wilson, Samuel H. . Modulating the DNA polymerase β reaction equilibrium to dissect the reverse reaction.

Miura, Fumihito; Fujino, Tomoko; Kogashi, Kanako; Shibata, Yukiko; Miura, Miki; Isobe, Hiroyuki; Ito, Takashi . Triazole linking for preparation of a next-generation sequencing library from single-stranded DNA.

Roda, Barbara; Marassi, Valentina; Zattoni, Andrea; Borghi, Francesco; Anand, Resmi; Agostoni, Valentina; Gref, Ruxandra; Reschiglian, Pierluigi; Monti, Sandra . Flow field-flow fractionation and multi-angle light scattering as a powerful tool for the characterization and stability evaluation of drug-loaded metal-organic framework nanoparticles.

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