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5-Aminoallylcytidine-5'-Triphosphate - (N-1065)

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This product is now available upon request as a custom synthesis. It is not maintained as a stocked item.

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5-Aminoallylcytidine-5’-triphosphate (AA-CTP) can be used in the same biochemical and diagnostic applications as 5-Aminoallyluridine-5’-triphosphate (AA-UTP) (Silverman et al., Bruning et al.). AA-CTP is a good substrate for RNA polymerase and leads to a higher transcription yield of 5-aminoallyl residues than the use of AA-UTP (Baum et al.). After transcription, 5-aminoallyl-C residues can be labeled with a fluorescent dye, biotin or other functional group through amino conjugation. AA-CTP can also be labeled or modified prior to transcription as modified-AA-CTP derivatives are typically substrates for RNA polymerase.
Product details
Catalog No N-1065
Purity ≥90% by AX-HPLC
Extinction Coefficient 5,041 Lmol-1cm-1 at 290 nm
Molecular Formula C12H21N4O14P3 (free acid)
Molecular Weight 538.20 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H2O
Recommended Storage -20°C or below
Other Name(s) 5-AA-CTP
Application Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Backbone 5'-Triphosphate
Base Analog(s) Cytidine
Sugar Type(s) RNA
Nucleotide Category Base Modified RNA
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N-1065 Safety Data Sheet

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