5-Aminoallylcytidine-5’-triphosphate (AA-CTP) can be used in the same biochemical and diagnostic applications as 5-Aminoallyluridine-5’-triphosphate (AA-UTP) (Silverman et al., Bruning et al.). AA-CTP is a good substrate for RNA polymerase and leads to a higher transcription yield of 5-aminoallyl residues than the use of AA-UTP (Baum et al.). After transcription, 5-aminoallyl-C residues can be labeled with a fluorescent dye, biotin or other functional group through amino conjugation.
AA-CTP can also be labeled or modified prior to transcription as modified-AA-CTP derivatives are typically substrates for RNA polymerase.
Product Details
Catalog No
N-1065
Purity
≥90% by AX-HPLC
Extinction Coefficient
5,041 Lmol-1cm-1 at 290 nm
Molecular Formula
C12H21N4O14P3 (free acid)
Molecular Weight
538.20 g/mole (free acid)
Salt Form
Li+
Concentration
100 mM
Buffer
H2O
Recommended Storage
-20°C or below
Other Name(s)
5-AA-CTP
Application
Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
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