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  5. 5-Fluoro-2'-deoxyuridine-5'-Triphosphate

5-Fluoro-2'-deoxyuridine-5'-Triphosphate - (N-2022)

5-F-dUTP, 5-Fl-dUTP, 5-Fluoro-dUTP
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Product Details

Catalog No N-2022
Purity ≥90% by AX-HPLC
Extinction Coefficient 7,350 Lmol-1cm-1 at 268 nm
Molecular Formula C9H14N2O14P3F (free acid)
Molecular Weight 486.10 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H2O
Recommended Storage -20°C or below
Other Name(s) 5-F-dUTP, 5-Fl-dUTP, 5-Fluoro-dUTP
Application Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Backbone 5'-Triphosphate
Base Analog(s) Thymidine, Uridine
Sugar Type(s) DNA
Nucleotide Category Base Modified DNA

Technical Documents

N-2022 Safety Data Sheet

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Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission of Seller. No license under any patent or other intellectual property right of Seller or its licensors is granted or implied by the purchase unless otherwise provided in writing.

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2'-Deoxynucleoside-5'-Triphosphate Set - (N-2505)

References

Wood, David O.; Dinsmore, Michael J.; Bare, Grant A.; Lee, Jeremy S. . M-DNA is stabilised in G*C tracts or by incorporation of 5-fluorouracil.

Zhang, Xuemei; Motea, Edward; Lee, Irene; Berdis, Anthony J. . Replication of a Universal Nucleobase Provides Unique Insight into the Role of Entropy during DNA Polymerization and Pyrophosphorolysis

Baehr, Carly A.; Huntoon, Catherine J.; Hoang, Song-My; Jerde, Calvin R.; Karnitz, Larry M. . Glycogen Synthase Kinase 3 (GSK-3)-mediated Phosphorylation of Uracil N-Glycosylase 2 (UNG2) Facilitates the Repair of Floxuridine-induced DNA Lesions and Promotes Cell Survival.

Yoon, Sorah; Huang, Kai-Wen; Reebye, Vikash; Spalding, Duncan; Przytycka, Teresa M.; Wang, Yijie; Swiderski, Piotr; Li, Lin; Armstrong, Brian; Reccia, Isabella; Zacharoulis, Dimitris; Dimas, Konstantinos; Kusano, Tomokazu; Shively, John; Habib, Nagy; Rossi, John J. . Aptamer-Drug Conjugates of Active Metabolites of Nucleoside Analogs and Cytotoxic Agents Inhibit Pancreatic Tumor Cell Growth.

Zeng, Xuehuo; Hernandez-Sanchez, Wilnelly; Xu, Mengyuan; Whited, Tawna L.; Baus, Diane; Zhang, Junran; Berdis, Anthony J.; Taylor, Derek J. . Administration of a Nucleoside Analog Promotes Cancer Cell Death in a Telomerase-Dependent Manner.

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