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Catalog Products
Nucleoside Triphosphates & Nucleotides
Base Modified NTPs
5-Fluoro-2'-deoxyuridine-5'-Triphosphate
5-Fluoro-2'-deoxyuridine-5'-Triphosphate - (N-2022)
5-F-dUTP, 5-Fl-dUTP, 5-Fluoro-dUTP
Product Details
Catalog No
N-2022
Purity
≥90% by AX-HPLC
Extinction Coefficient
7,350 Lmol-1 cm-1 at 268 nm
Molecular Formula
C9 H14 N2 O14 P3 F (free acid)
Molecular Weight
486.10 g/mole (free acid)
Salt Form
Li+
Concentration
100 mM
Buffer
H2 O
Recommended Storage
-20°C or below
Other Name(s)
5-F-dUTP, 5-Fl-dUTP, 5-Fluoro-dUTP
Application
Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Backbone
5'-Triphosphate
Base Analog(s)
Thymidine, Uridine
Sugar Type(s)
DNA
Nucleotide Category
Base Modified DNA
Intellectual Property
Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission of Seller. No license under any patent or other intellectual property right of Seller or its licensors is granted or implied by the purchase unless otherwise provided in writing.
TriLink does not warrant that the use or sale of the products delivered hereunder will not infringe the claims of any United States or other patents or patents pending covering the use of the product alone or in combination with other products or in the operation of any process. All and any use of TriLink product is the purchaser's sole responsibility.
References
Wood, David O.; Dinsmore, Michael J.; Bare, Grant A.; Lee, Jeremy S. . M-DNA is stabilised in G*C tracts or by incorporation of 5-fluorouracil.
Zhang, Xuemei; Motea, Edward; Lee, Irene; Berdis, Anthony J. . Replication of a Universal Nucleobase Provides Unique Insight into the Role of Entropy during DNA Polymerization and Pyrophosphorolysis
Baehr, Carly A.; Huntoon, Catherine J.; Hoang, Song-My; Jerde, Calvin R.; Karnitz, Larry M. . Glycogen Synthase Kinase 3 (GSK-3)-mediated Phosphorylation of Uracil N-Glycosylase 2 (UNG2) Facilitates the Repair of Floxuridine-induced DNA Lesions and Promotes Cell Survival.
Yoon, Sorah; Huang, Kai-Wen; Reebye, Vikash; Spalding, Duncan; Przytycka, Teresa M.; Wang, Yijie; Swiderski, Piotr; Li, Lin; Armstrong, Brian; Reccia, Isabella; Zacharoulis, Dimitris; Dimas, Konstantinos; Kusano, Tomokazu; Shively, John; Habib, Nagy; Rossi, John J. . Aptamer-Drug Conjugates of Active Metabolites of Nucleoside Analogs and Cytotoxic Agents Inhibit Pancreatic Tumor Cell Growth.
Zeng, Xuehuo; Hernandez-Sanchez, Wilnelly; Xu, Mengyuan; Whited, Tawna L.; Baus, Diane; Zhang, Junran; Berdis, Anthony J.; Taylor, Derek J. . Administration of a Nucleoside Analog Promotes Cancer Cell Death in a Telomerase-Dependent Manner.
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