5-Iodouridine-5'-Triphosphate - (N-1012)
5-Iodo-UTP
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N-1012
Description
An NTP for incorporation of a photoreactive base. Useful for RNA/protein crosslinking applications
Product details
Catalog No | N-1012 |
---|---|
Purity | ≥90% by AX-HPLC |
Extinction Coefficient | 6,533 Lmol-1cm-1 at 287 nm |
Molecular Formula | C9H14N2O15P3I (free acid) |
Molecular Weight | 610.00 g/mole (free acid) |
Salt Form | Li+ |
Concentration | 100 mM |
Buffer | H2O |
Recommended Storage | -20°C or below |
Other Name(s) | 5-Iodo-UTP |
Application | Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies |
Backbone | 5'-Triphosphate |
Base Analog(s) | Uridine |
Sugar Type(s) | RNA |
Nucleotide Category | Base Modified RNA |
Technical documents
N-1012 Safety Data Sheet
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Certificate of analysis
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Intellectual property
Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission of Seller. No license under any patent or other intellectual property right of Seller or its licensors is granted or implied by the purchase unless otherwise provided in writing.
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References
- Ito, Nobutoshi; Nureki, Osamu; Shirouzu, Mikako; Yokoyama, Shigeyuki; Hanaoka, Fumio . Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis
- Bley, Christopher J.; Qi, Xiaodong; Rand, Dustin P.; Borges, Chad R.; Nelson, Randall W.; Chen, Julian J.-L. . RNA-protein binding interface in the telomerase ribonucleoprotein.
- Kanwar, Jagat R.; Roy, Kislay; Kanwar, Rupinder K. . Chimeric aptamers in cancer cell-targeted drug delivery.